News tagged with protein degradation

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Old Cells Work Differently

Biology / Cell & Microbiology

created Mar 01, 2009 | popularity 4.3 / 5 (3) | comments 0

The agglutination and accumulation of proteins in nerve cells are major hallmarks of age-related neurodegenerative illnesses such as Alzheimer's disease. Cellular survival thus depends on a controlled removal of excessive ...


Probing and Controlling ‘Molecular Rattling’ May Mean Better Preservatives

Probing and Controlling 'Molecular Rattling' May Mean Better Preservatives

Chemistry / Polymers

created Feb 25, 2009 | popularity 5 / 5 (8) | comments 0

(PhysOrg.com) -- For centuries, people have preserved fruit by mixing it with sugar, making thick jams that last for months without spoiling. Now scientists at the National Institute of Standards and Technology ...


Why Fruits Ripen and Flowers Die: Salk Scientists Discover How Key Plant Hormone is Triggered

Why fruits ripen and flowers die: Scientists discover how key plant hormone is triggered

Biology /

created Feb 10, 2009 | popularity 5 / 5 (1) | comments 0

Best known for its effects on fruit ripening and flower fading, the gaseous plant hormone ethylene shortens the shelf life of many fruits and plants by putting their physiology on fast-forward. In recent years, ...


Space mission for worms

Space & Earth / Space Exploration

created Jan 15, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Worms from The University of Nottingham should be checking in for a flight onboard the Space Shuttle later this year — to help researchers investigate the effect of zero gravity on the body's muscle development ...





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Unraveling how cells respond to low oxygen

Medicine & Health / Research

created Aug 05, 2009 | popularity not rated yet | comments 0

Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. The REDD1 protein is a critical inhibitor of the mTOR signaling pathway, ...


Mechanism explains link between apolipoprotein E and Alzheimer's disease

Medicine & Health / Research

created Jun 11, 2008 | popularity not rated yet | comments 0

Scientists have discovered a previously unknown mechanism by which apolipoprotein E, a molecule whose mutation is linked to Alzheimer's disease (AD), stimulates degradation of sticky amyloid beta (A-beta) protein within the ...


Key protein that may cause cancer cell death identified

Biology /

created Jan 16, 2009 | popularity 5 / 5 (2) | comments 1

Researchers at A*STAR's Institute of Molecular and Cell Biology (IMCB) have become the first to discover and characterize a human protein called Bax-beta (Baxβ), which can potentially cause the death of cancer cells ...


Enzyme for ubiquitin-dependent protein degradation linked to cellular senescence

Biology /

created May 22, 2008 | popularity 5 / 5 (1) | comments 0

A new study, published by Cell Press in the May 23rd issue of the journal Molecular Cell, identifies a pivotal role for the CUL7 E3 ubiquitin ligase in growth control. The research makes an exciting new connection betwee ...


Egg P bodies protect maternal gene messages

Biology /

created Aug 11, 2008 | popularity 3.7 / 5 (3) | comments 0

A cell decides what proteins to make based on the messages it receives from its genome. Sometimes messages are held back to be read later, and in most cell types these delayed messages are stored and eventually marked for ...


Images of Neurons in Culture

Scientists make headway in understanding Alzheimer's disease

Medicine & Health / Research

created Feb 05, 2009 | popularity 4.6 / 5 (5) | comments 0

Scientists at UC Santa Barbara have discovered that a protein called BAG2 is important for understanding Alzheimer's disease and may open up new targets for drug discovery. They are ready to move from studying ...


Researchers discover cell's 'quality control' mechanism

Biology /

created Jul 29, 2008 | popularity 4.9 / 5 (8) | comments 2

Researchers in Japan and Canada have discovered a key component of the quality control mechanism that operates inside human cells – sometimes too well. The breakthrough has significant implications for the development of ...


Researchers make new finding about how memory is stored

Medicine & Health / Research

created Apr 23, 2008 | popularity 4.4 / 5 (7) | comments 0

Researchers at Wake Forest University School of Medicine are the first to show that the location of protein-destroying “machines” in nerve cells in the brain may play an important role in how memories are formed – a finding ...


Biologists identify key protein in cell's 'self-eating' function

Biology /

created Mar 11, 2008 | popularity 5 / 5 (1) | comments 0

Molecular biologists at the University of California, San Diego have found one piece of the complex puzzle of autophagy, the process of “self-eating” performed by all eukaryotic cells -- cells with a nucleus -- to keep themselves ...


Chopped up proteins trigger autoimmunity

Medicine & Health / Research

created Jan 24, 2008 | popularity 3.5 / 5 (2) | comments 0

Multipotent adult progenitor stem cells extracted from bone marrow, and known as MAPCs, have proved to be effective in the regeneration of blood vessel tissue and also in muscle tissue when treating peripheric vascular disease.



List of search results for protein degradation