A new artificial intelligence (AI) tool that draws logical inferences about the function of unknown proteins promises to help scientists unravel the inner workings of the cell.
Molecular & Computational biology
Feb 14, 2024
0
217
Penn Engineers have pioneered a new way to visualize the smallest protein clusters, skirting the physical limitations of light-powered microscopes and opening new avenues for detecting the proteins implicated in diseases ...
Biotechnology
Feb 8, 2024
0
55
When it comes to drug development, membrane proteins play a crucial role, with about 50% of drugs targeting these molecules. Understanding the function of these membrane proteins, which connect to the membranes of cells, ...
Cell & Microbiology
Feb 8, 2024
0
39
Protein degraders, a novel approach in drug discovery, show promise in tackling diseases previously thought to be untreatable. Unlike traditional drugs that block specific protein functions, degraders alter the cell's natural ...
Biochemistry
Jan 30, 2024
0
8
Designed to meet the urgent need for insights into the molecular intricacies of SARS-CoV-2 infection, BioExcel-CV19 is a repository for molecular dynamics (MD) simulations.
Molecular & Computational biology
Jan 8, 2024
0
49
Cell replication in our bodies is triggered by a cascade of molecular signals transmitted between proteins. Compounds that block these signals when they run amok show potential as cancer drugs.
Molecular & Computational biology
Jan 8, 2024
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4
Neurodegenerative disorders such as Alzheimer's disease affect more than 270 million people worldwide. AD is the leading cause of dementia, resulting in memory loss due to atrophy of neurons in the hippocampus, which is the ...
Bio & Medicine
Jan 4, 2024
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94
Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal ...
Cell & Microbiology
Jan 2, 2024
0
66
Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to be maintained within a ...
Biotechnology
Jan 2, 2024
0
155
For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat surfaces or require ...
Biochemistry
Dec 28, 2023
0
203
