News tagged with protein kinase inhibitors
Targeted agent shows promise in biliary cancer study
Apr 20, 2009 |
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An experimental agent has shown promising results in people with advanced biliary cancer, according to a multi-institutional clinical trial led by cancer researchers at the Ohio State University.
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Enzyme may create new approach to hypertension therapy
Dec 17, 2009 |
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New research from the Northwestern University Feinberg School of Medicine has found that an alternative therapy may be possible for treating some types of hypertension using an enzyme called ACE2.
Invasion without a stir
Dec 17, 2009 |
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Bacteria of the genus Salmonella cause most food-borne illnesses. The bacteria attach to cells of the intestinal wall and induce their own ingestion by cells of the intestinal epithelium. Up till now, researchers assumed ...
Low cholesterol transfer protein activity associated with heart disease risk
Dec 15, 2009 |
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Although seen as a potential heart disease therapy, raising high-density lipoprotein (HDL) cholesterol levels by inhibiting activity of a transfer protein may not be effective, a new study suggests. Scientists at the Jean ...
Scientists Uncover Protective Mechanism Against Liver Cancer
Dec 14, 2009 |
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(PhysOrg.com) -- A team of scientists from the UC San Diego School of Medicine and Osaka University in Japan have identified a protein switch that helps prevent liver damage, including inflammation, fibrosis and cancer. The ...
Mechanism discovered by which body's cells encourage tuberculosis infection
Dec 10, 2009 |
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Scientists have discovered a signaling pathway that tuberculosis bacteria use to coerce disease-fighting cells to switch allegiance and work on their behalf. Epithelial cells line the airways and other surfaces ...
Study Describes Novel Model of Skin Cancer
Dec 09, 2009 |
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(PhysOrg.com) -- Scientists at the University of Pennsylvania School of Medicine have developed a new model of skin cancer based on the knowledge that a common cancer-related molecule called Src kinase is ...
A new mouse could help understand how some lung cancer cells evade drug treatment
Dec 09, 2009 |
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Lung cancer is the leading cause of cancer mortality worldwide and lung adenocarcinoma is the most common type. Many cases of lung adenocarcinoma are attributed to a mutation in a gene for the epidermal growth factor receptor ...
Most antidepressants miss key target of clinical depression
Medicine & Health / Psychology & Psychiatry
Dec 08, 2009 |
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A key brain protein called monoamine oxidase A (MAO-A) - is highly elevated during clinical depression yet is unaffected by treatment with commonly used antidepressants, according to an important study published today in ...
Undergrad researchers lay groundwork for drug addiction remedy
Dec 08, 2009 |
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Sarah Steele and Langtian "Ren" Yuan were both self-admittedly inexperienced Duke freshmen in the spring of 2006. But then they followed helpful directions of an assistant chemistry professor, added their own patience and ...
Parasite evades death by promoting host cell survival
Dec 08, 2009 |
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Researchers have discovered how the parasite Trypanosoma cruzi, which causes Chagas' disease, prolongs its survival in infected cells. A protein on the parasite activates the enzyme Akt, which blocks cell ...
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