News tagged with protein misfolding
Inhibitor of Heat Shock Protein is a Potential Anticancer Drug, Study Finds
Oct 29, 2009 |
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(PhysOrg.com) -- Like yoga for office drones, cells do have coping strategies for stress. Heat, lack of nutrients, oxygen radicals - all can wreak havoc on the delicate internal components of a cell, potentially ...
Scientists find a biological 'fountain of youth' in new world bat caves
Jun 30, 2009 |
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Scientists from Texas are batty over a new discovery which could lead to the single most important medical breakthrough in human history -- significantly longer lifespans. The discovery, featured on the cover of the July ...
Key to pre-eclampsia may be found in misfolded proteins in the urine
Jan 30, 2009 |
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Clues to the cause of preeclampsia, a common, but serious hypertension complication of pregnancy that has puzzled doctors and researchers for decades, point to proteins that misfold and aggregate, according to Yale School ...
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Misfolded proteins: The fundamental problem is aging
Aug 24, 2009 |
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Proteins are essential for all biological activities and the health of the cell. Misfolded and damaged proteins spell trouble and are common to all human neurodegenerative diseases and many other age-associated diseases. ...
Fish oil protects against diseases like Parkinson's, study
Apr 19, 2009 |
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Dr. Nicolas Bazan, Director of the Neuroscience Center of Excellence, Boyd Professor, and Ernest C. and Yvette C. Villere Chair of Retinal Degenerative Diseases Research at LSU Health Sciences Center New Orleans, will present ...
Structural biology scores with protein snapshot
Jun 25, 2009 |
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In a landmark technical achievement, investigators in the Vanderbilt Center for Structural Biology have used nuclear magnetic resonance (NMR) methods to determine the structure of the largest membrane-spanning ...
Study leads to a promising first-in-class drug candidate
Jul 21, 2009 |
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Discoveries by Scripps Research Institute scientists have led to a promising new drug candidate--the first in its class--for patients with a genetic protein-misfolding disease. In results announced by the biopharmaceutical ...
Animal study suggests inadequate sleep may exacerbate cellular aging in the elderly
Jun 27, 2008 |
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Researchers at the University of Pennsylvania School of Medicine have shown that the unfolded protein response, which is a reaction to stress induced by sleep deprivation, is impaired in the brains of old mice.
Computer simulations point to key molecular basis of cystic fibrosis
Biology /
Mar 01, 2008 |
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Researchers from the University of North Carolina at Chapel Hill have identified a key molecular mechanism that may account for the development of cystic fibrosis, which about 1 in 3000 children are born with in the US every ...
Unfolding 'nature's origami'
Mar 02, 2009 |
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Sometimes known as "nature's origami", the way that proteins fold is vital to ensuring they function correctly. But researchers at the University of Leeds have discovered this is a 'hit and miss' process, with proteins potentially ...
Parkinson's protein protects neurons from stress induced cell death
May 21, 2007 |
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The scientists could show that Parkin prevents the induction of neuronal cell death. As reported in the Journal of Neuroscience, the protein activates a survival mechanism which had been known for its prominent role in imm ...
Promising research on the susceptibility to and drug targets for Parkinson's disease
Mar 21, 2008 |
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Better understanding of Parkinson’s disease onset during aging is important for improving diagnostics and developing strategies for therapeutic intervention. Scientists from the University Medical Center in Groningen have ...
Dysfunctional protein dynamics behind neurological disease?
Medicine & Health / Neuroscience
Oct 13, 2009 |
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Researchers at Lund University, Sweden, have taken a snapshot of proteins changing shape, sticking together and creating structures that are believed to trigger deadly processes in the nervous system. The discovery opens ...
List of search results for protein misfolding
