News tagged with protein p53
Researchers pinpoint a new enemy for tumor-suppressor p53
Jun 26, 2009 |
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Researchers at The University of Texas M. D. Anderson Cancer Center have identified a protein that marks the tumor suppressor p53 for destruction, providing a potential new avenue for restoring p53 in cancer ...
New research on the 'guardian of the genome'
May 12, 2009 |
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(PhysOrg.com) -- Protein p53 protects the body against cancer and is knocked out in many cancer tumours. Researchers at Karolinska Institutet have identified two molecules that can restore p53's cancer-killing properties. ...
Research shows cell's inactive state is critical for effectiveness of cancer treatment
Biology /
Jan 09, 2009 |
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A new study sheds light on a little understood biological process called quiescence, which enables blood-forming stem cells to exist in a dormant or inactive state in which they are not growing or dividing. According to the ...
Chemopreventive isothiocyanates selectively depletes mutant p53 in tumor cells
Apr 20, 2009 |
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Researchers at Lombardi Comprehensive Cancer Center at Georgetown University Medical Center have demonstrated that naturally-occurring compounds can selectively deplete mutant p53 and restore "wild type" function to p53 in ...
Most common brain cancer may originate in neural stem cells
Jun 01, 2009 |
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University of Michigan scientists have found that a deficiency in a key tumor suppressor gene in the brain leads to the most common type of adult brain cancer. The study, conducted in mice that mimic human cancer, points ...
Loss of Tumor-Suppressor and DNA-Maintenance Proteins Causes Tissue Demise, Study Finds
Oct 15, 2009 |
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(PhysOrg.com) -- A study published in the October issue of Nature Genetics demonstrates that loss of the tumor-suppressor protein p53, coupled with elimination of the DNA-maintenance protein ATR, severely disrup ...
