News tagged with randomized controlled trials
Validity of cost-effectiveness models based on randomized clinical trials
Dec 08, 2009 |
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Cost-effectiveness studies are widely used to guide prescribing policy in many countries, as part of health technology assessment programmes. However, a new study published this week in PLoS Medicine by Tjeerd-Pieter van St ...
Some discrepancies exist between outcomes indicated in trial registration and later publications
Sep 01, 2009 |
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Comparison of the primary outcomes of registered clinical trials with their subsequent publication appears to show some discrepancies, according to a study in the September 2 issue of JAMA.
Research: Improving treatment of patients with heart attack
Jun 25, 2009 |
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When faced with patients suffering a heart attack, doctors have two choices: inject them with medication to dissolve the blood clot (fibrinolytic therapy) or insert a small balloon to open the blocked artery (primary percutaneous ...
Search results for randomized controlled trials
Deficiencies common in radiation therapy trial reports for Hodgkin’s, non-Hodgkin's lymphoma
Feb 04, 2009 |
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Reporting of radiation therapy details in randomized controlled trials for Hodgkin's and non-Hodgkin's lymphoma is deficient due to a lack of reporting of key radiation therapy descriptors and quality assurance processes ...
Vitamins C and E and beta carotene again fail to reduce cancer risk in randomized controlled trial
Dec 31, 2008 |
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Women who took beta carotene or vitamin C or E or a combination of the supplements had a similar risk of cancer as women who did not take the supplements, according to data from a randomized controlled trial in the December ...
Radiofrequency treatment better than ethanol injection for small liver tumors
Feb 03, 2009 |
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A new review of four randomized controlled trials that directly compared two different treatments for small inoperable liver tumors has found that radiofrequency ablation (RFA) significantly improves patient survival compared ...
Adding antiviral agents to steroids to treat facial paralysis is not linked to improved recovery
Jun 15, 2009 |
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Adding an antiviral agent to corticosteroids for treatment of Bell's palsy (a condition characterized by partial facial paralysis) is not associated with improved recovery of facial movement function, according to a meta-analysis ...
Cancer treatments in phase 3 trials successful up to half of the time
Mar 24, 2008 |
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About one-fourth to one-half of new cancer treatments that reach assessment in phase 3 randomized clinical trials are eventually proven successful, according to a report in the March 24 issue of Archives of Internal Medicine, one of ...
Analysis of drug-eluting stents data demonstrates safety, efficacy in on-and-off-label use
Jun 16, 2009 |
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The Cardiovascular Research Foundation (CRF) announced that results of the largest meta-analysis to date comparing mortality rates for drug-eluting stents (DES) versus bare metal stents (BMS) were published online June 15 ...
Findings challenge common practice regarding glucose control for critically ill patients
Aug 26, 2008 |
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An analysis of randomized trials indicates that for critically ill adults, tight glucose control is not associated with a significantly reduced risk of death in the hospital, but is associated with an increased risk of hypoglycemia, ...
Penn study shows how electronic medical records can be used to test drug efficacy
Feb 06, 2009 |
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For years controversy has surrounded whether electronic medical records (EMR) would lead to increased patient safety, cut medical errors, and reduce healthcare costs. Now, researchers at the University of Pennsylvania School ...
ARDS mortality is unchanged since 1994
Jan 23, 2009 |
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Mortality in patients with acute respiratory distress syndrome (ARDS) has not fallen since 1994, according to a comprehensive review of major studies that assessed ARDS deaths. This disappointing finding contradicts the common ...
Doubts cast on credibility of some published clinical trials
Jul 02, 2009 |
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Randomised Controlled Trials (RCTs) are considered the 'gold standard' research method for assessing new medical treatments. But research published in BioMed Central's open access journal Trials shows that the design of a r ...
List of search results for randomized controlled trials
