Sirolimus
hideSirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. A macrolide, sirolimus was first discovered as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island — an island also known as "Rapa Nui", hence the name. It is marketed under the trade name Rapamune by Wyeth.
Sirolimus was originally developed as an antifungal agent. However, this was abandoned when it was discovered that it had potent immunosuppressive and antiproliferative properties.
For more information about Sirolimus, read the full article at
Wikipedia.
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News tagged with rapamycin
HIV uses autophagy for its own means
Medicine & Health / HIV & AIDS
Jul 27, 2009 |
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Not satisfied with simply thwarting its host's defensive maneuvers, HIV actually twists one to its advantage, based on new findings from Kyei et al. in the July 27, 2009 issue of the Journal of Cell Biology. Vojo D ...
Longevity pill on the horizon?
Jul 10, 2009 |
4.4 / 5 (17) |
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(PhysOrg.com) -- While applauding findings that an Easter Island compound extends the lives of middle-aged mice, University of Washington longevity researchers caution that healthy people shouldn't start taking the drug in ...
Grapefruit juice boosts drug's anti-cancer effects
Apr 20, 2009 |
4.6 / 5 (7) |
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In a small, early clinical trial, researchers at the University of Chicago Medical Center have found that combining eight ounces of grapefruit juice with the drug rapamycin can increase drug levels, allowing lower doses of ...
Researchers Formulate Treatment Combination Lethal To Pancreatic Cancer Cells (w/Video)
Apr 20, 2009 |
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A combination of two targeted therapies packs a powerful punch to kill pancreatic cancer cells in the laboratory, Mayo Clinic cancer researchers report. With further testing of these drugs that are from classes of pharmaceuticals ...
Cancer-causing gene discovery suggests new therapies
Jan 24, 2009 |
5 / 5 (5) |
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Scientists have discovered a novel way by which a much-studied cancer-promoting gene accelerates the disease. The finding suggests a new strategy to halt cancer's progress.
