News tagged with rapamycin
Novel drug combination offers therapeutic promise for hard-to-treat cancers
Researchers at Brigham and Women's Hospital (BWH) have identified a new combination of targeted therapies that, together, may treat two aggressive tumor types that until now have not had effective treatments. These findings ...
Sep 12, 2011 |
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Inhibition of microRNAs can stimulate the growth of new blood vessels
This is the result of a recent experimental study carried out at the University Hospital Freiburg in Germany and funded by the German Research Foundation. In an animal model of peripheral artery disease, blood flow to the ...
Medicine & Health / Cardiology
Aug 29, 2011 |
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Possible new drug for children with progeria
(Medical Xpress) -- A new study published in the journal Science Translational Medicine shows that rapamycin and its derivative everolimus, which is currently used to treat cancer and transplant rejections, may wo ...
Jun 30, 2011 |
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Renal cancer drug temsirolimus shows promise against mesothelioma
A drug commonly used to treat kidney cancer may increase the effectiveness of chemotherapy for mesothelioma, according to a study published in the May issue of the Journal of Thoracic Oncology.
May 01, 2011 |
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Red wine compound increases anti-tumor effect of rapamycin
Cleveland – Researchers from Cleveland Clinic's Lerner Research Institute have discovered that resveratrol – a compound found in red wine – when combined with rapamycin can have a tumor-suppressing effect on ...
Feb 14, 2011 |
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Discovery may aid search for anti-aging drugs
A team of University of Michigan scientists has found that suppressing a newly discovered gene lengthens the lifespan of roundworms. Scientists who study aging have long known that significantly restricting food intake makes ...
Aug 18, 2010 |
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Perhaps a longer lifespan, certainly a longer 'health span'
Organisms from yeast to rodents to humans all benefit from cutting calories. In less complex organisms, restricting calories can double or even triple lifespan. It's not yet clear just how much longer calorie restriction ...
Apr 15, 2010 |
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Research discovery may lead to advances in heart disease and cancer treatment
Research led by T. Cooper Woods, PhD, Assistant Professor of Pharmacology and Experimental Therapeutics at LSU Health Sciences Center New Orleans, and Director of the Molecular Cardiology Research Laboratory at Ochsner Clinic ...
Apr 14, 2010 |
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A drug that extends life span prevents Alzheimer's deficits
If research results continue to be repeated and are turned into clinical trials, a drug already approved for some uses could be marshaled -- sooner than we expect -- to prevent Alzheimer's disease in humans and improve health ...
Apr 01, 2010 |
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Research points to potential treatment for kidney disease
Research performed at UC Santa Barbara points to the drug rapamycin as a potential treatment for kidney disease. The study builds on past research and shows that studies performed on mice are more likely to ...
Jan 25, 2010 |
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HIV uses autophagy for its own means
Not satisfied with simply thwarting its host's defensive maneuvers, HIV actually twists one to its advantage, based on new findings from Kyei et al. in the July 27, 2009 issue of the Journal of Cell Biology. Vojo D ...
Medicine & Health / HIV & AIDS
Jul 27, 2009 |
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Longevity pill on the horizon?
(PhysOrg.com) -- While applauding findings that an Easter Island compound extends the lives of middle-aged mice, University of Washington longevity researchers caution that healthy people shouldn't start taking the drug in ...
Jul 10, 2009 |
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Grapefruit juice boosts drug's anti-cancer effects
In a small, early clinical trial, researchers at the University of Chicago Medical Center have found that combining eight ounces of grapefruit juice with the drug rapamycin can increase drug levels, allowing lower doses of ...
Apr 20, 2009 |
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Researchers Formulate Treatment Combination Lethal To Pancreatic Cancer Cells (w/Video)
A combination of two targeted therapies packs a powerful punch to kill pancreatic cancer cells in the laboratory, Mayo Clinic cancer researchers report. With further testing of these drugs that are from classes of pharmaceuticals ...
Apr 20, 2009 |
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Cancer-causing gene discovery suggests new therapies
Scientists have discovered a novel way by which a much-studied cancer-promoting gene accelerates the disease. The finding suggests a new strategy to halt cancer's progress.
Jan 24, 2009 |
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Sirolimus
Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. A macrolide, sirolimus was first discovered as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island — an island also known as "Rapa Nui", hence the name. It is marketed under the trade name Rapamune by Wyeth.
Sirolimus was originally developed as an antifungal agent. However, this was abandoned when it was discovered that it had potent immunosuppressive and antiproliferative properties.
For more information about Sirolimus, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
