News tagged with receptor genes
New tumor suppressor gene identified
A recent study published in Clinical Cancer Research suggests that the protein hVps37A suppresses tumor growth in ovarian cancer. The work, which was funded by the Austrian Science Fund FWF, shows, for th ...
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Mechanism sheds light on how the brain adapts to stress
Scientists now have a better understanding of the way that stress impacts the brain. New research, published by Cell Press in the January 26 issue of the journal Neuron, reveals pioneering evidence for a new mechanism of str ...
Medicine & Health / Neuroscience
Jan 25, 2012 |
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The link between TB and a gene mutation that causes lung cancer
Tuberculosis (TB) has been suspected to increase a person's risk of lung cancer because the pulmonary inflammation and fibrosis can induce genetic damage. However, direct evidence of specific genetic changes and the disease ...
Jan 18, 2012 |
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Studies help clarify the role of lapatinib and trastuzumab in treating HER2 positive breast cancer
In patients with HER2-positive breast cancer, Tykerb (lapatinib) has been used both in combination with herceptin (trastuzumab) and as an alternative single-agent therapy for pre-surgery (neo-adjuvant) chemotherapy treatment. ...
Jan 16, 2012 |
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Finding the silent killer -- a biomarker test for atherosclerosis
Furring of the arteries, atherosclerosis, is a leading cause of death across the world. Atherosclerosis leads to peripheral arterial disease, coronary heart disease, stroke and heart attacks. However, atherosclerosis is a ...
Jan 13, 2012 |
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Exercise in a pill may protect against extreme heat sensitivity
We've all seen the story in the news before. Whether it's the death of a physically fit high school athlete at football training camp in August, or of an elderly woman gardening in the middle of the day in July, heat stroke ...
Jan 08, 2012 |
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NanoCAGE reveals transcriptional landscape of the mouse main olfactory epithelium
The problem in biology of how to identify the promoters of olfactory receptor genes (>1000 genes) has remained unsolved due to the difficulty of purifying sufficient material from the olfactory epithelium. ...
Jan 05, 2012 |
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Signaling to chromatin
(Medical Xpress) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI) in collaboration with their colleagues from the Department of Biosystems Science and Engineering of the ETH ...
Jan 03, 2012 |
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A gene that protects against colorectal cancers
The research team in France has developed an animal model carrying a mutation of the DCC gene. Mice carrying the mutation develop tumours, because this gene can no longer induce the death of the cancer cells. This discovery ...
Dec 14, 2011 |
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Proteins do not predict outcome of herceptin treatment in HER2-positive breast cancer
Precisely quantifying the amount of three different HER growth proteins, along with several other proteins believed linked to breast cancer, did not predict a patient's outcome after treatment for HER2-Positive Breast Cancer ...
Dec 09, 2011 |
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Breast cancer type linked to paternal cancer
The risk of breast cancer is increased by genetic and lifestyle factors such as the inherited BRCA2 gene, age of having first child, or use of hormone replacement therapy (HRT). New research published in BioMed Central's ...
Nov 28, 2011 |
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Mice with fewer insulin-signaling receptors don't live longer
Scientists studying longevity thought it might be good to lack a copy of a gene, called IGF1 receptor, that is important in insulin signaling. Previous studies showed invertebrates that lacked the copy lived longer, even ...
Nov 23, 2011 |
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Cannabinoid receptor 1 is linked to dependence on alcohol and other substances
While researchers know that genetic factors play an important role in the development of alcohol dependence (AD), it is challenging to discover which particular genes may be involved. Prior evidence had established that the ...
Nov 15, 2011 |
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Gene impedes recovery from alcoholism
People who are alcohol-dependent and who also carry a particular variant of a gene run an increased risk of premature death. This is a recent finding from the interdisciplinary research at the Department of Psychology and ...
Nov 15, 2011 |
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Gene switch for odorant receptors
The olfactory sensory neurons in the nasal mucosa perceive the myriad smells in the air with the aid of odorant receptors. Each sensory neuron chooses one and only one receptor gene for expression. The probability ...
Nov 11, 2011 |
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