Scientists identify first negative regulator of NOX4 translation

Nicotinamide adenine dinucleotide phosphate oxidase 4 (NADPH oxidase 4, NOX4) is an important member of the NADPH oxidase family that is primarily responsible for the production of H2O2. The regulation of NOX4 activity is ...

Gene expression technology set to semi-automation

The Human Genome Project generated the first sequence of the human genome, revealing a kind of blueprint of human biology. Two decades later, the field of gene regulatory networks describes a complex system where thousands ...

How does a bacterium know it's time to split apart?

Bacterial cells do not wake up one morning and decide to become parents. But there is a point in their cell cycle—after growing sufficiently and replicating their genomes—when they split in two, creating new cells that ...

Biomolecular condensates: Regulatory hubs for plant iron supply

Iron is a micronutrient for plants. Biologists from the Institute of Botany at Heinrich Heine University Düsseldorf (HHU) describe in a study, which has now been published in the Journal of Cell Biology, that regulatory ...

Researchers define new class of regulatory element in DNA

Researchers at the MRC Weatherall Institute of Molecular Medicine's Laboratory of Gene Regulation, led by Professor Doug Higgs and Dr. Mira Kassouf, have published a study in the journal Cell, in which they reveal another ...

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