A study uncovers the 'grammar' behind human gene regulation

A research group at the University of Helsinki has discovered the logic that controls gene regulation in human cells. In the future, this new knowledge could be used for investigating cancers and other genetic diseases.

Illuminating dark matter in human DNA

Researchers at University of California San Diego have produced a single-cell chromatin atlas for the human genome. Chromatin is a complex of DNA and protein found in eukaryotic cells; regions of chromatin at key gene regulatory ...

Mapping of genetic control elements in the cerebellum

The mammalian cerebellum has long been associated almost exclusively with motor control, yet recent studies indicate that it also contributes to many higher brain functions. An international research team led by Prof. Dr. ...

Understanding what drives cell typing

Scientists know that developing cells in a healthy embryo will transform into a variety of cell types that will make up the different organ systems in the human body, a process known as cell differentiation. But they don't ...

Scientists identify networks for spikelet formation in barley

Organ development in plants mostly occurs through combinatorial activity of so-called meristems. Meristems are plant cells or tissues that give rise to new organs, similar to stem cells in human—including spikelets. Spikelets ...

Sixty-year-old question on DNA replication timing sequence answered

Over the last 60 years, scientists have been able to observe how and when genetic information was replicated, determining the existence a "replication timing program," a process that controls when and in what order segments ...

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