News tagged with repair genes
Joint patent for using the BRCA1 gene as a therapy for cardiovascular disease
St. Michael's Hospital and King Saud University have received their first joint U.S. patent to use the BRCA1 gene as a therapy for cardiovascular disease.
Feb 10, 2012 |
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How protein networks stabilize muscle fibers: Same mechanism as for DNA
The same mechanism that stabilises the DNA in the cell nucleus is also important for the structure and function of vertebrate muscle cells. This has been established by RUB-researchers led by Prof. Dr. Wolfgang Linke (Institute ...
Jan 23, 2012 |
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Breast cancer and heart disease may have common roots
Women who are at risk for breast cancer may also be at greater risk for heart disease, new research has found.
Dec 20, 2011 |
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'PARP' drug sabotages DNA repair in pre-leukemic cells
Looking for ways to halt the uncontrolled growth of cancer cells, scientists at Johns Hopkins have found that a new class of drugs, called PARP inhibitors, may block the ability of pre-leukemic cells to repair broken bits ...
Dec 12, 2011 |
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A question of gene silencing
When investigating cancer cells, researchers discovered numerous peculiarities: Particular RNA molecules are present in large numbers, particular genes are overactive. Do these characteristics have a relation to cancer? Do ...
Aug 24, 2011 |
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Olaparib shows promise in treating ovarian cancer, even without BRCA mutations
The PARP inhibitor, olaparib, that has shown promise in women with an inherited mutation in their BRCA1 or BRCA2 gene (accounting for about 5-10% of breast and ovarian cancer cases), has, for the first time, been shown to ...
Aug 21, 2011 |
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Progressive telomere shortening characterizes familial breast cancer patients
Telomeres, the complex structures that protect the end of chromosomes, of peripheral blood cells are significantly shorter in patients with familial breast cancer than in the general population. Results of the study carried ...
Jul 29, 2011 |
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Heads or tails? Worm with abundant ability to regenerate relies on ancient gene to make decisions
(PhysOrg.com) -- Most people don’t think worms are cool. But the tiny flatworm that Northwestern University scientist Christian Petersen studies can do something very cool indeed: it can regenerate itself from nearly ...
May 17, 2011 |
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Gene find could aid nerve repair
Scientists have pinpointed a gene that controls how quickly a person’s nerves can regenerate after injury or disease.
Apr 12, 2011 |
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Light, circadian rhythms affect vast range of physiological, behavioral functions
A new study of the genetic basis of circadian rhythms - the biological responses related to daily light exposure - has found that a few minutes of light exposure in a fungus directly affects a huge range of its biological ...
Aug 26, 2010 |
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Protein made by breast cancer gene purified
A key step in understanding the origins of familial breast cancer has been made by two teams of scientists at the University of California, Davis. The researchers have purified, for the first time, the protein produced by ...
Aug 22, 2010 |
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New drug reduces tumor size in women with advanced hereditary ovarian or breast cancer
Understanding the underlying genetic weakness of certain types of cancer may lead to targeted therapy and provide the key to effective treatment, a new study suggests. An international consortium of researchers has shown ...
Aug 12, 2010 |
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Researchers identify a new breast and ovarian cancer susceptibility gene
A group of researchers report evidence unambiguously implicating the gene RAD51C in susceptibility to breast and ovarian cancer. This gene normally plays a role in DNA repair. By screening RAD51C in unrelated individuals ...
Apr 21, 2010 |
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Survival of the healthiest: Selective eradication of malignant cells
The ultimate goal in cancer research, a treatment that kills cancer cells whilst leaving healthy cells untouched, is brought nearer by the success of a new therapeutic approach. The potential therapy, published in BioMed ...
Nov 05, 2009 |
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Gene therapy repairs injured human donor lungs for the first time
For the first time, scientists in the McEwen Centre for Regenerative Medicine, University Health Network have successfully used gene therapy to repair injured human donor lungs, making them potentially suitable ...
Oct 28, 2009 |
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