News tagged with repair


Stopgap DNA repair needs a second step

Chemistry / Biochemistry

created May 04, 2009 | popularity 5 / 5 (1) | comments 0

One can have a dream, two can make that dream so real, goes a popular song. Now a Weizmann Institute study has revealed that it takes two to perform an essential form of DNA repair.


Upside-down world: DNA protecting protein helps cancer drug to kill cells

Biology / Cell & Microbiology

created Apr 28, 2009 | popularity 4.5 / 5 (2) | comments 0

Some DNA repair enzymes can become double-edged swords - If they work too slowly, they can block necessary cell maintenance and contribute to cell death. This could explain the somewhat mysterious success of the widely used ...


Scientists identify key decision-point at which cells with broken DNA repair themselves or die

Chemistry / Biochemistry

created Apr 10, 2009 | popularity 5 / 5 (1) | comments 1

When cells undergo potentially catastrophic damage, for example as a result of exposure to ionizing radiation, they must make a decision: either to fix the damage or program themselves for death, a process called apoptosis.


DNA repair mechanisms relocate in response to stress

Biology / Cell & Microbiology

created Mar 26, 2009 | popularity 5 / 5 (1) | comments 0

Like doctors making house calls, some DNA repair enzymes can relocate to the part of the cell that needs their help, a collaborative team of scientists at Emory University School of Medicine has found.


Researchers Identify New Protein Important in Breast Cancer Gene's Role in DNA Repair

Researchers Identify New Protein Important in Breast Cancer Gene's Role in DNA Repair

Medicine & Health / Cancer

created Mar 17, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- For years, researchers have known that under normal conditions, the breast cancer protein BRCA1 orchestrates the repair of damaged DNA, but the details of just how BRCA1 moves to the damaged ...


DNA differences may influence risk of Hodgkin disease

Medicine & Health / Cancer

created Mar 09, 2009 | popularity not rated yet | comments 0

A new analysis has found that certain variations in genes that repair DNA can affect a person's risk of developing Hodgkin disease. Published in the April 1, 2009 issue of CANCER, a peer-reviewed journal of the American Cancer ...


Team combats antibiotic resistance with engineered viruses

Biology / Cell & Microbiology

created Mar 02, 2009 | popularity 5 / 5 (2) | comments 0

A new approach to fighting bacterial infections, developed at MIT and Boston University, could help prevent bacteria from developing antibiotic resistance and help kill those that have already become resistant.


Study identifies new gene associated with ALS

Medicine & Health / Genetics

created Feb 26, 2009 | popularity 5 / 5 (1) | comments 0

A collaborative research effort spanning nearly a decade between researchers at Massachusetts General Hospital (MGH) and King’s College London (KCL) has identified a novel gene for inherited amyotrophic lateral sclerosis ...


How cells handle broken chromosomes

Chemistry /

created Feb 13, 2009 | popularity 4.5 / 5 (2) | comments 0

(PhysOrg.com) -- After being recognized and initially processed by the cellular machinery, the broken chromosome is extensively scanned for homology and the break itself is later tethered to the nuclear envelope. Thus the ...


Animal eggs not suitable substitutes to produce stem cells

Biology /

created Feb 02, 2009 | popularity 3 / 5 (1) | comments 0

Since the cloning of Dolly the Sheep over a decade ago, somatic cell nuclear transfer (SCNT) has been considered a promising way to generate human, patient-specific stem cells for therapeutic applications. The shortage of ...


DNA Repair

Human DNA repair process recorded in action (Video)

Biology /

created Jan 29, 2009 | popularity 4.8 / 5 (11) | comments 0

(PhysOrg.com) -- A key phase in the repair process of damaged human DNA has been observed and visually recorded by a team of researchers at the University of California, Davis. The recordings provide new information ...


Study shows how defective DNA repair triggers 2 neurological diseases

Medicine & Health / Genetics

created Jan 15, 2009 | popularity not rated yet | comments 0

Scientists at St. Jude Children's Research Hospital have teased apart the biological details distinguishing two related neurological diseases—ataxia telangiectasia-like disease (ATLD) and Nijmegen breakage syndrome (NBS).


Abnormal DNA repair genes may predict pancreatic cancer risk

Medicine & Health / Cancer

created Jan 15, 2009 | popularity not rated yet | comments 0

Abnormalities in genes that repair mistakes in DNA replication may help identify people who are at high risk of developing pancreatic cancer, a research team from The University of Texas M. D. Anderson Cancer Center reports ...


Glitches in DNA repair genes predict prognosis in pancreatic cancer

Medicine & Health / Cancer

created Jan 14, 2009 | popularity 5 / 5 (1) | comments 0

Variations in mismatch repair genes can help predict treatment response and prognosis in patients with pancreatic cancer, according to research from The University of Texas M. D. Anderson Cancer Center presented today in ...


'Smart scaffolds' may help heal broken hearts

Medicine & Health / Research

created Jan 12, 2009 | popularity 5 / 5 (2) | comments 0

Canadian researchers have, for the first time, developed an organic substance that attracts and supports cells necessary for tissue repair and can be directly injected into problem areas. This development, published online ...