RNA—in the form of messenger RNA (mRNA), ribosomal RNA (rRNA), and transfer RNA (tRNA)—transforms the genome coded by DNA into proteins that form the backbone of all cellular functions. However, biochemical modifications ...
Cell & Microbiology
Apr 8, 2024
0
25
The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job of knocking out genes to cure hereditary disease. But it's still not possible to insert whole genes ...
Biotechnology
Feb 20, 2024
0
148
Trypanosome is a single-celled parasite that takes an extensive human and economic toll due to its involvement in causing sleeping sickness in humans and a similar disease in cattle. The parasite, found mainly in rural areas ...
Cell & Microbiology
Dec 19, 2023
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3
Arabidopsis thaliana is a species grown worldwide for genetic research and was the first plant to have its complete set of chromosomes (its genome) sequenced.
Molecular & Computational biology
Dec 16, 2023
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362
Aldehydes are toxic compounds that are produced in the body by metabolic processes, especially upon alcohol consumption. They are dangerous because they bind to cellular macromolecules, such as DNA, RNA, and proteins, and ...
Cell & Microbiology
Nov 15, 2023
0
9
Bacteria are nearly ubiquitous and have tremendous impacts on human and ecological health. And yet, they remain largely mysterious to us. Princeton MOL faculty Zemer Gitai, Britt Adamson and Ned Wingreen launched a joint ...
Cell & Microbiology
Sep 14, 2023
0
20
The mechanisms of RNA-binding proteins (RBPs)-mediated post-transcriptional regulation of pre-existing mRNAs, which is essential for spermatogenesis, remain poorly understood.
Cell & Microbiology
Jul 25, 2023
0
1
Life runs on ribosomes. Every cell on Earth needs ribosomes to translate genetic information into all the proteins needed for the organism to function—and to in turn make more ribosomes. But scientists still lack a clear ...
Cell & Microbiology
Jul 6, 2023
0
402
Scientists at St. Jude Children's Research Hospital revealed that human ribosomes decode messenger RNA (mRNA) 10 times slower than bacterial ribosomes, but do so more accurately. The study, published today in Nature, used ...
Cell & Microbiology
Apr 5, 2023
0
52
Antibiotic resistance (ARE) is a threat to human health worldwide, as diverse proteins allow pathogenic bacteria to develop increasing levels of resistance to antibiotic medicines. Now, a team from the University of Tsukuba ...
Cell & Microbiology
Mar 30, 2023
0
4
