The Achilles heel of the coronavirus

Viruses require the resources of an infected cell to replicate and then infect further cells, and transfer to other individuals. One essential step in the viral life cycle is the production of new viral proteins based on ...

New method expands the world of small RNAs

A team led by a biomedical scientist at the University of California, Riverside, has developed a new RNA-sequencing method— "Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing," or PANDORA-seq—that ...

Mechanism discovered how the coronavirus hijacks the cell

Researchers at ETH Zurich and the University of Bern have discovered a mechanism by which the corona virus manipulates human cells to ensure its own replication. This knowledge will help to develop drugs and vaccines against ...

Scientists discover new rules about 'runaway' transcription

On the evolutionary tree, humans diverged from yeast roughly 1 billion years ago. By comparison, two seemingly similar species of bacteria, Escherichia coli and Bacillus subtilis, have been evolving apart for roughly twice ...

Binding sites for protein-making machinery

ETH Zurich researchers can predict how tightly a cell's protein synthesis machinery will bind to RNA sequences—even when dealing with many billions of different RNA sequences. This binding plays a key role in determining ...

Anatomy of an acne treatment

Sarecycline, a drug approved for use in the United States in 2018, is the first new antibiotic approved to treat acne in more than 40 years. Now, researchers at Yale and the University of Illinois-Chicago have discovered ...

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