News tagged with ribosome
Watching the engine of life, in real time, to understand how things go wrong
(PhysOrg.com) -- Ruben Gonzalez views ribosomes—the minute particles in cells that make proteins—as the “machines” of life. Naturally, the associate professor of chemistry is interested ...
Jan 31, 2012 |
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Biologists uncover a novel cellular proofreading mechanism
(PhysOrg.com) -- To make proteins, cells assemble long chains of amino acids, based on genetic instructions from DNA. That construction takes place in a tiny cellular structure called a ribosome, to which amino acids are ...
Nov 11, 2011 |
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Detailed view of a crucial enzymatic complex revealed
Researchers led by ETH professor Nenad Ban have now completed the three-dimensional structure of the ribosome from a higher organism. This structure will increase the understanding of this cellular “protein ...
Nov 07, 2011 |
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Three-part handoff delivers proteins to membrane surface
The delivery system for an important class of proteins in the cell membrane can be fully replicated with a mere three components, according to a new study.
Aug 24, 2011 |
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Scientists expand knowledge of cell process involved in many diseases
As part of a joint research effort with the University of Michigan, scientists from the Florida campus of The Scripps Research Institute have for the first time defined the structure of one of the cell's most basic engines, ...
Aug 16, 2011 |
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Scientists explain unique activity of TB drug pyrazinamide
Pyrazinamide has been used in combination with other drugs as a first-line treatment for people with tuberculosis (TB) since the 1950s, but exactly how the drug works has not been well understood.
Aug 11, 2011 |
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Computer simulations aid understanding of bacterial resistance against commonly used antibiotics
A recent study into the interactions between aminoglycoside antibiotics and their target site in bacteria used computer simulations to elucidate this mechanism and thereby suggest drug modifications.
Jul 21, 2011 |
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Atomic-scale structures of ribosome could help improve antibiotics
(PhysOrg.com) -- It sounds like hype from a late-night infomercial: It can twist and bend without breaking! And wait, there's more: It could someday help you fend off disease!
May 19, 2011 |
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From gene to protein: Gene expression quantification offers new insights
How do genes control us? This fundamental question of life still remains elusive despite decades of research. Genes are blueprints for proteins, but it is the proteins that actually carry out vital functions in the body for ...
May 18, 2011 |
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New finding in ribosome signaling may lead to improved antibiotics
(PhysOrg.com) -- Researchers at the University of Illinois at Chicago have discovered a signaling mechanism in the bacterial ribosome that detects proteins that activate genes for antibiotic resistance.
Feb 23, 2011 |
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Scientist uncovers switch controlling protein production
A scientist from the Florida campus of The Scripps Research Institute has discovered a molecular switch that controls the synthesis of ribosomes. Ribosomes are the large machineries inside all living cells that produce proteins, ...
Dec 22, 2010 |
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How cells export and embed proteins in the membrane
Like an overprotective parent on the first day of school, a targeting factor sometimes needs a little push to let go of its cargo. Scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, ...
Dec 13, 2010 |
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Working in concert
As cells go about the process of building new proteins, each amino acid gets delivered individually to the protein-synthesizing machinery of the ribosome by a specialized transfer RNA (tRNA) molecule. This ...
Dec 06, 2010 |
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Scientists ratchet up understanding of cellular protein factory
(PhysOrg.com) -- Theoretical biologists at Los Alamos National Laboratory have used a New Mexico supercomputer to aid an international research team in untangling another mystery related to ribosomes -- those ...
Dec 02, 2010 |
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The eukaryotic ribosome unveils its structure
One year after the Nobel Prize in chemistry was awarded for the discovery of the bacterial ribosome's atomic structure, French researchers from the Institut de Genetique et de Biologie Moleculaire et Cellulaire ...
Dec 01, 2010 |
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