The untapped potential of RNA structures

The human genome has just over 20,000 genes coding for proteins. Yet, it produces at least ten times that many different non-coding RNA molecules, which can often take on more than one shape. At least some of this RNA structurome ...

Researchers develop new tool for targeted cell control

Thanks to new RNA vaccines, we humans have been able to protect ourselves incredibly quickly from new viruses like SARS-CoV-2, the virus that causes COVID-19. These vaccines insert a piece of ephemeral genetic material into ...

'Kipferl': Guiding the defense against jumping genes

A large part of our DNA is made up of selfish repetitive DNA elements, some of which can jump from one site in the genome to another, potentially damaging the genome. Researchers from the Institute of Molecular Biotechnology ...

Scientists discover dual-function messenger RNA

For the very first time, a study led by Julian Chen and his group in Arizona State University's School of Molecular Sciences and the Biodesign Institute's Center for the Mechanism of Evolution, has discovered an unprecedented ...

Scientists develop new technique to reveal the hidden genome

Using an innovative new technique, scientists at Duke-NUS Medical School and their collaborators have identified thousands of previously unknown DNA sequences in the human genome that code for microproteins and peptides potentially ...

First mouse model with mitochondrial tRNALeu mutation developed

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial ...

Artificial intelligence folds RNA molecules

For the function of many biomolecules, their three-dimensional structure is crucial. Researchers are therefore not only interested in the sequence of the individual building blocks of biomolecules, but also in their spatial ...

Exploring new roles for non-coding RNA

The past decade has seen enormous advances in the understanding of regulatory noncoding RNAs, according to a Northwestern Medicine review published in Molecular Cell.

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