News tagged with rna polymerase

Study uncovers how DNA unfolds for transcription

(PhysOrg.com) -- The human genome contains some 3 billion base pairs that are tightly compacted into the nucleus of each cell. If a DNA strand were the thickness of a human hair, the entire human genome would ...

Biology / Cell & Microbiology

created Jan 17, 2012 | popularity 5 / 5 (4) | comments 5 | with audio podcast

Transcriptional elongation control takes on new dimensions

Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in ...

Biology / Cell & Microbiology

created Dec 22, 2011 | popularity 5 / 5 (1) | comments 0

Structure of a molecular copy machine: How mitochondrial genes are transcribed

Mitochondria are compartments within cells and have their own DNA. The key protein required for the expression of the genetic information in this DNA is the mitochondrial RNA polymerase enzyme. Its three-dimensional structure ...

Biology / Cell & Microbiology

created Sep 26, 2011 | popularity 5 / 5 (1) | comments 0

Dundee researchers make gene breakthrough

Researchers at the University of Dundee have made a significant breakthrough in understanding how human cells decode genes important for cell growth and multiplication.

Biology / Biotechnology

created Sep 16, 2011 | popularity 5 / 5 (2) | comments 0

Proteins enable essential enzyme to maintain its grip on DNA

Scientists have identified a family of proteins that close a critical gap in an enzyme that is essential to all life, allowing the enzyme to maintain its grip on DNA and start the activation of genes.

Biology / Cell & Microbiology

created Jul 21, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Ready, go!

Just like orchestra musicians waiting for their cue, RNA polymerase II molecules are poised at the start site of many developmentally controlled genes, waiting for the "Go!"- signal to read their part of the ...

Biology / Cell & Microbiology

created Jul 14, 2011 | popularity not rated yet | comments 0

Researcher maps far-reaching effects of estrogen signaling in breast cancer cells

A UT Southwestern Medical Center researcher has identified the most comprehensive measurement to date of estrogen's effect on breast cancer cells, showing for the first time how immediate and extensive the effect is.

Medicine & Health / Cancer

created May 05, 2011 | popularity not rated yet | comments 0 | with audio podcast

Scientists observe single gene activity in living cells

Researchers at Albert Einstein College of Medicine of Yeshiva University have for the first time observed the activity of a single gene in living cells. In an unprecedented study, published in the April 22 online edition ...

Biology / Biotechnology

created Apr 21, 2011 | popularity 4.2 / 5 (5) | comments 0 | with audio podcast

Want to silence a gene? Pull here

(PhysOrg.com) -- Simply stretching DNA can silence a gene, scientists at the UA have discovered. The finding could point to a previously unknown gene control mechanism.

Biology / Biotechnology

created Mar 21, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Stop and go: How the cell deals with transcriptional roadblocks

Gene transcription is central to cell function, as it converts the information stored in the DNA into RNA molecules of defined sequence, which then program protein synthesis. The enzyme RNA polymerase II (Pol II) is responsible ...

Biology / Cell & Microbiology

created Feb 23, 2011 | popularity not rated yet | comments 0 | with audio podcast

UM scientists demonstrate role of RNA polymerase in gene transcription

In all organisms, RNA synthesis is carried out by proteins - known as RNA polymerases (RNAPs) - that transcribe the genetic information from DNA in a highly-regulated, multi-stage process. RNAP is the key enzyme involved ...

Biology / Biotechnology

created Jul 15, 2010 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Correcting a trick of the light brings molecules into view

Conventional wisdom holds that optical microscopy can't be used to "see" something as small as an individual molecule. But as it is wont, clever science has once again overturned conventional wisdom. Secretary ...

Nanotechnology / Nanophysics

created Jul 14, 2010 | popularity 5 / 5 (20) | comments 1 | with audio podcast

The 3-dimensional transcription film

Gene expression takes place in two stages: the transcription of DNA to RNA by an enzyme called RNA polymerase, followed by the translation of this RNA into proteins, whose behaviour affects the characteristics of each individual.

Chemistry / Biochemistry

created Jun 17, 2010 | popularity 5 / 5 (2) | comments 0

How the wrong genes are repressed

The mechanism by which 'polycomb' proteins critical for embyronic stem cell function and fate are targeted to DNA has been identified by UCL scientists.

Biology / Cell & Microbiology

created Jun 11, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Physics of gene transcription unveiled

(PhysOrg.com) -- A research team has made precise measurements of where and how RNA polymerase encounters obstacles while it reads nucleosomal DNA.

Biology / Cell & Microbiology

created May 14, 2010 | popularity 5 / 5 (12) | comments 2 | with audio podcast

RNA polymerase

RNA polymerase (RNAP or RNApol) is an enzyme that produces RNA. In cells, RNAP is needed for constructing RNA chains from DNA genes as templates, a process called transcription. RNA polymerase enzymes are essential to life and are found in all organisms and many viruses. In chemical terms, RNAP is a nucleotidyl transferase that polymerizes ribonucleotides at the 3' end of an RNA transcript.

For more information about RNA polymerase, read the full article at Wikipedia.
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