Getting dynamic information from static snapshots
Imagine predicting the exact finishing order of the Kentucky Derby from a still photograph taken 10 seconds into the race.
Imagine predicting the exact finishing order of the Kentucky Derby from a still photograph taken 10 seconds into the race.
Molecular & Computational biology
Apr 27, 2024
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70
Researchers at Karolinska Institutet have developed a web-based platform that offers an unprecedented view of the human body at the cellular level. The aim is to create an invaluable resource for researchers worldwide to ...
Cell & Microbiology
Apr 25, 2024
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2
If a tree falls in the forest—whether or not anyone registers the sound—one thing is for sure: there are lots of fungi around. Within a forest's soil, hundreds of species decompose debris, mobilize nutrients from that ...
Ecology
Apr 24, 2024
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180
Researchers have found that tiny particles present in cows' milk could offer, for the first time, an effective method for the oral delivery of RNA drugs.
Bio & Medicine
Apr 24, 2024
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1
Despite huge advances in our understanding of COVID-19 over the past four years, the disease is still very much among us—and there remains a lot to learn.
Cell & Microbiology
Apr 24, 2024
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28
A team of researchers at IOCB Prague led by Prof. Michal Hocek has developed a novel method for preparing ribonucleic acid (RNA) containing modified bases. Innovative use of engineered DNA polymerases, enzymes commonly used ...
Biotechnology
Apr 23, 2024
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14
Dysregulated R-loops can cause stalled replication forks and telomere instability. However, how R-loops are recognized and regulated, is still not well understood, particularly at telomeres.
Cell & Microbiology
Apr 22, 2024
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19
Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development ...
Cell & Microbiology
Apr 18, 2024
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20
The beginning of life on Earth and its evolution over billions of years continue to intrigue researchers worldwide. The central dogma or the directional flow of genetic information from a deoxyribose nucleic acid (DNA) template ...
Molecular & Computational biology
Apr 18, 2024
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141
The technology used to sequence SARS-CoV-2 at record speed early in the COVID-19 pandemic has been successfully tested as a technique to monitor arboviruses and diseases transmitted mainly by mosquitoes.
Biotechnology
Apr 17, 2024
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8
Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate. RNA is very similar to DNA, but differs in a few important structural details: in the cell, RNA is usually single-stranded, while DNA is usually double-stranded; RNA nucleotides contain ribose while DNA contains deoxyribose (a type of ribose that lacks one oxygen atom); and RNA has the base uracil rather than thymine that is present in DNA.
RNA is transcribed from DNA by enzymes called RNA polymerases and is generally further processed by other enzymes. RNA is central to the synthesis of proteins. Here, a type of RNA called messenger RNA carries information from DNA to structures called ribosomes. These ribosomes are made from proteins and ribosomal RNAs, which come together to form a molecular machine that can read messenger RNAs and translate the information they carry into proteins. There are many RNAs with other roles – in particular regulating which genes are expressed, but also as the genomes of most viruses.
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