A team led by Chris Sullivan, a professor of molecular biosciences at The University of Texas at Austin, has provided the first positive evidence that RNA interference (RNAi), a biological process in which small RNA molecules ...
Cell & Microbiology
Oct 15, 2013
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Scientists have a promising new approach to combating deadly human viruses thanks to an educated hunch by University of California, Riverside microbiology professor Shou-Wei Ding, and his 20 years of research on plants, fruit ...
Cell & Microbiology
Oct 10, 2013
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Silencing genes that have malfunctioned is an important approach for treating diseases such as cancer and heart disease. One effective approach is to deliver drugs made from small molecules of ribonucleic acid, or RNA, which ...
Bio & Medicine
Jul 9, 2013
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What makes one Argonaute a slicer and another one not? Human Argonaute proteins are key players in the gene regulation process known as RNA interference, RNAi. Professor Joshua-Tor's group of Cold Spring Harbor Laboratory ...
Cell & Microbiology
Jun 6, 2013
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Researchers at the Whitehead Institute and Memorial Sloan-Kettering Cancer Center have defined and analyzed the crystal structure of a yeast Argonaute protein bound to RNA. This complex plays a key role in the RNA interference ...
Cell & Microbiology
Jun 20, 2012
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Scientists at The Scripps Research Institute have determined the three-dimensional atomic structure of a human protein that is centrally involved in regulating the activities of cells. Knowing the precise structure of this ...
Biochemistry
Apr 26, 2012
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Scientists at the Max Planck Institute for Chemical Ecology, Germany, are now using a procedure which brings forward ecological research on insects: They study gene functions in moth larvae by manipulating genes using the ...
Biotechnology
Feb 2, 2012
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A cell's genome maintains its integrity by organizing some of its regions into a super-compressed form of DNA called heterochromatin. In the comparatively simple organism fission yeast, a cellular phenomenon known as RNA ...
Cell & Microbiology
Nov 13, 2011
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At the same time that a cell's DNA gets duplicated, a third of it gets super-compacted into repetitive clumps called heterochromatin. This dense packing serves to repress or "silence" the DNA sequences within -- which could ...
Cell & Microbiology
Oct 16, 2011
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Viruses have numerous tricks for dodging the immune system. In the September 7, 2009 issue of the Journal of Cell Biology, Stagg et al. reveal a key detail in one of these stratagems, identifying a protein that enables cyto-megalovirus ...
Cell & Microbiology
Aug 31, 2009
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