The Scripps Research Institute

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The Scripps Research Institute (TSRI) is a medical research facility that focuses on research in the basic biomedical sciences. Primarily located in La Jolla, California, with a sister facility in Jupiter, Florida, the institute is home to 3,000 scientists, technicians, graduate students, and administrative and other staff, making it among the largest private, non-profit biomedical research organizations in the world.

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Two distinct molecular pathways can make regulatory immune cells

Biology / Cell & Microbiology

created Mar 03, 2009 | popularity 5 / 5 (1) | comments 0

Finding a way to bypass the molecular events involved in autoimmunity - where the body's immune system mounts a self-directed attack - could lead to new treatments for autoimmune disorders and chronic infections. A study ...


Scientists find new structural motif in key enzymes is essential to prevent autoimmune disease

Medicine & Health / Research

created Jan 16, 2009 | popularity not rated yet | comments 0

Scientists from the Scripps Research Institute and the Genomics Institute of the Novartis Research Foundation have found a specific mutation that leads to the development of severe autoimmune kidney disease in mice. The research ...


Researchers develop new technique to tap full potential of antibody libraries

Medicine & Health / Cancer

created Jan 15, 2009 | popularity not rated yet | comments 0

In hopes of more fully tapping the libraries' potential, a group of Scripps Research Institute scientists, led by Scripps Research President Richard A. Lerner, M.D., has for the first time developed a new screening technique ...


Scientists develop first examples of RNA that replicates itself indefinitely

Chemistry /

created Jan 09, 2009 | popularity 4.9 / 5 (12) | comments 24

Now, a pair of Scripps Research Institute scientists has taken a significant step toward answering that question. The scientists have synthesized for the first time RNA enzymes that can replicate themselves without the help ...





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Brain's endocannabinoid signaling pathway kept in check by two enzymes

Medicine & Health / Research

created Nov 25, 2009 | popularity 4.2 / 5 (5) | comments 2

(PhysOrg.com) -- A research team has shown that blocking the degradation of two naturally occurring cannabinoids in the endocannabinoid signaling pathway of the brain produces marijuana-like behavioral effects in mice, according ...


Scientists find new link between insulin and core body temperature

Medicine & Health / Diseases

created Nov 19, 2009 | popularity 5 / 5 (1) | comments 0

A team led by scientists at The Scripps Research Institute have discovered a direct link between insulin—a hormone long associated with metabolism and metabolic disorders such as diabetes—and core body temperature. While ...


The bizarre lives of bone-eating worms

Biology / Plants & Animals

created Nov 09, 2009 | popularity 4.5 / 5 (2) | comments 0

The females of the recently discovered Osedax marine worms feast on submerged bones via a complex relationship with symbiotic bacteria, and they are turning out to be far more diverse and widespread than scientists expected. ...


Diet switching can activate brain's stress system, lead to 'withdrawal' symptoms

Medicine & Health / Research

created Nov 09, 2009 | popularity 5 / 5 (2) | comments 0

In research that sheds light on the perils of yo-yo dieting and repeated bouts of sugar-bingeing, researchers from The Scripps Research Institute have shown in animal models that cycling between periods of eating sweet and ...


Facebook for scientists: Map your expertise

Facebook for scientists: Map your expertise

Technology / Computer Sciences

created Oct 27, 2009 | popularity 4 / 5 (1) | comments 0

(PhysOrg.com) -- Indiana University has received more than $1.8 million from the National Institutes of Health to collaborate on a $12.2 million, seven-university project designed to network researchers around ...


Physical scientists will apply laws of physics in cancer fight

Medicine & Health / Cancer

created Oct 26, 2009 | popularity 4 / 5 (1) | comments 0

Instead of killing cancer cells, researchers at Arizona State University will use the laws of physics to figure out how to control them. And, rather than treating cancer as a disease and seeking a cure, ASU scientists will ...


Scientists reveal secrets of drought resistance

Biology / Plants & Animals

created Oct 22, 2009 | popularity 5 / 5 (8) | comments 0

A team of biologists in California led by researchers at The Scripps Research Institute and the University of California, San Diego has solved the structure of a critical molecule that helps plants survive during droughts. ...


Studies improve knowledge of underlying brain changes caused by addiction

Medicine & Health / Neuroscience

created Oct 21, 2009 | popularity not rated yet | comments 0

New research using animal models is enabling a deeper understanding of the neurobiology of compulsive drug addiction in humans — knowledge that may lead to more effective treatment options to weaken the powerful cravings ...


Compound shows potential for slowing progression of ALS

Medicine & Health / Research

created Oct 19, 2009 | popularity not rated yet | comments 0

A chemical cousin of a drug currently used to treat sepsis dramatically slows the progression of amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, in mice. The results offer a bit of good news in ...


A major step in making better stem cells from adult tissue

Biology / Cell & Microbiology

created Oct 18, 2009 | popularity 4.9 / 5 (10) | comments 0

A team led by scientists from The Scripps Research Institute has developed a method that dramatically improves the efficiency of creating stem cells from human adult tissue, without the use of embryonic cells. The research ...



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