First CRISPR single-nucleotide edited transgenic mice

Cystic fibrosis, sickle cell anemia, Huntington's disease and phenylketonuria are all examples of disorders caused by the mutation of a single nucleotide, a building block of DNA. The human DNA consists of approximately 3 ...

Flowing toward red blood cell breakthroughs

A team of researchers from Brown University and ETH Zurich the Universita da Svizzera Italiana (USI) and Consiglio Nazionale delle Ricerche (CNR) is using America's largest, most powerful supercomputer to help understand ...

Genome-editing proteins seek and find with a slide and a hop

Searching a whole genome for one particular sequence is like trying to fish a specific piece from the box of a billion-piece puzzle. Using advanced imaging techniques, University of Illinois researchers have observed how ...

A turning point in the physics of blood

Mike Graham knows that fluid dynamics can reveal much about how the flow of blood helps and hinders individual blood cells as they go about their work.

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