Adverse effect
hideIn medicine, an adverse effect is a harmful and undesired effect resulting from a medication or other intervention such as surgery. An adverse effect may be termed a "side effect", when judged to be secondary to a main or therapeutic effect, and may result from an unsuitable or incorrect dosage or procedure, which could be due to medical error. Adverse effects are sometimes referred to as "iatrogenic" because they are generated by a physician/treatment. Some adverse effects only occur only when starting, increasing or discontinuing a treatment. Using a drug or other medical intervention which is contraindicated may increase the risk of adverse effects. Adverse effects may cause medical complications of a disease or procedure and negatively affect its prognosis. They may also lead to non-compliance with a treatment regimen.
The harmful outcome is usually indicated by some result such as morbidity, mortality, alteration in body weight, levels of enzymes, loss of function, or as a pathological change detected at the microscopic, macroscopic or physiological level. It may also be indicated by symptoms reported by a patient. Adverse effects may cause a reversible or irreversible change, including an increase or decrease in the susceptibility of the individual to other chemicals, foods, or procedures, such as drug interactions.
In clinical trials, a distinction is made between adverse events (AEs) and serious adverse events (SAEs). Generally, any event which causes death, permanent damage, birth defects, or requires hospitalization is considered an SAE. The results of these trials are often included in the labeling of the medication to provide information both for patients and the prescribing physicians.
For more information about Adverse effect, read the full article at
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News tagged with side effects
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Medicine & Health / Neuroscience
Dec 04, 2009 |
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Cannabis can reduce spasticity in multiple sclerosis (MS) patients. A systematic review, published in the open access journal BMC Neurology, found that five out six randomized controlled trials reported a reduction in spa ...
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Dec 07, 2009 |
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NEW ORLEANS ― The second-generation proteasome inhibitor carfilzomib is showing noteworthy response rates and low levels of adverse side effects among multiple myeloma patients in a phase II clinical trial, researchers ...
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Dec 07, 2009 |
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Glaxo's swine flu shot may give kids fever
Medicine & Health / Medications
Dec 04, 2009 |
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(AP) -- The European Medicines Agency warns that young children given GlaxoSmithKline's swine flu shot may get a fever after their second dose.
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Dec 03, 2009 |
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Even when women at high-risk of breast cancer are well-informed about the risks and benefits of using the drug tamoxifen for prevention, only 6 percent said they were likely to take it.
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Dec 01, 2009 |
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Results from a phase II clinical trial indicate a novel drug may provide a treatment option for chronic myeloid leukemia (CML) patients who do not respond to current therapies, researchers from The University of Texas M. ...
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Substituting cannabis in place of more harmful drugs may be a winning strategy in the fight against substance misuse. Research published in BioMed Central' open access Harm Reduction Journal features a poll of 350 cannab ...
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Dec 02, 2009 |
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Medicine & Health / Medications
Dec 01, 2009 |
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(AP) -- Drug giant GlaxoSmithKline says one of its swine flu vaccines has been certified by the World Health Organization, making it available for donors to buy for developing countries.
MSU researcher studies effects of experimental depression medication
Medicine & Health / Psychology & Psychiatry
Dec 02, 2009 |
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(PhysOrg.com) -- A Michigan State University researcher is leading a clinical trial on an experimental medication he hopes will give doctors another weapon in the fight against depression and prove to be more effective among ...
New safety concern related to antipsychotic treatment
Medicine & Health / Psychology & Psychiatry
Dec 01, 2009 |
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Overall, antipsychotic medications are reasonably effective, and fairly well tolerated treatments for mood and psychotic disorders. However, treatment with a number of antipsychotic medications is associated with weight ...
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