News tagged with signal pathways
Stress pathway identified as potential therapeutic target to prevent vision loss
A new study identifies specific cell-stress signaling pathways that link injury of the optic nerve with irreversible vision loss. The research, published by Cell Press in the February 9 issue of the journal Neuron, may le ...
Medicine & Health / Neuroscience
Feb 08, 2012 |
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A thought-provoking new therapeutic target for brain cancer?
Glioblastoma multiforme (GBM) is the most common of all malignant brain tumors that originate in the brain. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant ...
Feb 01, 2012 |
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Jak of all trades? Not of leukaemia therapy
About one in five or six cases of adult leukaemia in Western populations relates to so-called chronic myeloid leukaemia, or CML. Treatment of CML usually relies on inhibitors of the abnormal protein that causes the condition ...
Jan 30, 2012 |
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Gatekeeper signal controls skin inflammation
A new study unravels key signals that regulate protective and sometimes pathological inflammation of the skin. The research, published online on January 26th in the journal Immunity by Cell Press, identifies a "gatekeeper" that, ...
Jan 26, 2012 |
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Plant flavonoid luteolin blocks cell signaling pathways in colon cancer cells
Plant flavonoid luteolin blocks cell signaling pathways in colon cancer cells
Jan 23, 2012 |
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Signaling to chromatin
(Medical Xpress) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI) in collaboration with their colleagues from the Department of Biosystems Science and Engineering of the ETH ...
Jan 03, 2012 |
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Previously unconnected molecular networks conspire to promote cancer
An inflammation-promoting protein triggers deactivation of a tumor-suppressor that usually blocks cancer formation via the NOTCH signaling pathway, a team of researchers led by scientists at The University of Texas MD Anderson ...
Dec 22, 2011 |
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New discovery could lead to treatment for Angelman syndrome
Results of a new study from the University of North Carolina at Chapel Hill may help pave the way to a treatment for a neurogenetic disorder often misdiagnosed as cerebral palsy or autism.
Dec 21, 2011 |
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KS-herpesvirus induces reprogramming of lymphatic endothelial cells to invasive mesenchymal cells
Kaposi's sarcoma herpesvirus (KSHV) is an etiological agent for Kaposi's sarcoma and two other rare lymphoproliferative malignancies, and it is the most common cancer in HIV-infected untreated individuals. Researchers at ...
Dec 14, 2011 |
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Is obesity a ciliopathy, triggered by malfunctioning primary cilia?
Is obesity a ciliopathy, a disorder such as polycystic kidney disease (PKD), which is triggered by a defect in the microscopic hair-like cilia that protrude from virtually every cell of humans and other vertebrates?
Dec 06, 2011 |
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Aging human bodies and aging human oocytes run on different clocks
Reproductive and somatic aging use different molecular mechanisms that show little overlap between the types of genes required to keep oocytes healthy and the genes that generally extend life span, according to Coleen Murphy, ...
Dec 06, 2011 |
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Regeneration of specialized cells offers hope for treating chronic kidney disease
Damage to podocytes -- a specialized type of epithelial cell in the kidney -- occurs in more than 90 percent of all chronic kidney disease. Now researchers at the Stanford University School of Medicine have uncovered an unexpected ...
Dec 05, 2011 |
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New gene study of ADHD points to defects in brain signaling pathways
Pediatric researchers analyzing genetic influences in attention-deficit/hyperactivity disorder (ADHD) have found alterations in specific genes involved in important brain signaling pathways. The study raises the possibility ...
Medicine & Health / Psychology & Psychiatry
Dec 04, 2011 |
4 / 5 (5) |
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Unlocking the genetic and molecular mystery of soft-tissue sarcoma
Scientists at Joslin Diabetes Center in Boston have uncovered important molecular and genetic keys to the development of soft-tissue sarcomas in skeletal muscle, giving researchers and clinicians additional targets to stop ...
Nov 30, 2011 |
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Researcher creates neurons that light up as they fire
In a scientific first that potentially could shed new light on how signals travel in the brain, how learning alters neural pathways, and might lead to speedier drug development, scientists at Harvard have created genetically-altered ...
Medicine & Health / Neuroscience
Nov 29, 2011 |
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