News tagged with signaling


New method for detection of phosphoproteins reveals regulator of melanoma invasion

Medicine & Health / Research

created Apr 09, 2009 | popularity 5 / 5 (2) | comments 0

Scientists have developed a new approach for surveying phosphorylation, a process that is regulated by critical cell signaling pathways and regulates several key cellular signaling events. The research, published by Cell ...


High-fat diets plus extra protein make for bad mix

Biology / Cell & Microbiology

created Apr 07, 2009 | popularity 4 / 5 (5) | comments 0

It's basically a given that diets loaded with fat can lead to considerable health problems. But a new study in the April issue of Cell Metabolism, a Cell Press publication, shows that in some cases diets that are high in bot ...


Taking the conversation inside: Enhancing signals in cell interior

Medicine & Health / Research

created Mar 19, 2009 | popularity not rated yet | comments 0

Scientists used to think most of the exchange of information between cells was conducted at the surface, where cell receptors receive signals from other cells.


New target for heart failure therapy identified

Medicine & Health / Research

created Mar 16, 2009 | popularity 1 / 5 (1) | comments 0

A novel signaling pathway plays a significant role in the production of aldosterone, a hormone that promotes heart failure after a myocardial infarction, according to a study conducted by Thomas Jefferson University researchers.


New investigational treatment for bladder cancer

Medicine & Health / Cancer

created Mar 12, 2009 | popularity not rated yet | comments 0

A team of researchers, led by Columbia University Medical Center faculty, has identified a new investigational therapy for the treatment of bladder cancer. The discovery was made using a new research model, using mice, which ...


Capillary formation’s mechanical determinants: One growth factor can have many effects

Capillary formation’s mechanical determinants: One growth factor can have many effects

Medicine & Health / Research

created Mar 09, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- Harvard researchers have established a link between the growth of blood vessels and the mechanical stresses caused by the environment within which the vessels grow, a new understanding that ...


Researchers Identify Gene Linked to Aggressive Progression of Liver Cancer

Medicine & Health / Cancer

created Feb 17, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Virginia Commonwealth University researchers have identified a gene that plays a key role in regulating liver cancer progression, a discovery that could one day lead to new targeted therapeutic strategies ...


Tumor suppressor may attenuate fibrotic disease

Biology /

created Feb 17, 2009 | popularity not rated yet | comments 0

New research reveals a critical cellular signaling pathway that is responsible for generating excess connective tissue in multiple organs, similar to what is seen in human patients with scleroderma. The study, published by ...


Stem cell research uncovers mechanism for type 2 diabetes

Medicine & Health / Diseases

created Feb 12, 2009 | popularity 5 / 5 (2) | comments 0

Taking clues from their stem cell research, investigators at the University of California San Diego (UC San Diego) and Burnham Institute for Medical Research (Burnham) have discovered that a signaling pathway involved in ...


Lack of specific gene plays role in autism

Medicine & Health / Research

created Feb 09, 2009 | popularity not rated yet | comments 0

It is estimated that three to six out of every 1,000 children in the United States have autism - and the number of diagnosed cases is rising. Autism is one of a group of series developmental problems called autism spectrum ...


Possible drug target for obesity treatment a no-brainer: study

Medicine & Health / Research

created Feb 04, 2009 | popularity 4 / 5 (3) | comments 1

Scientists at the University of North Carolina at Chapel Hill School of Medicine have discovered a gene that when mutated causes obesity by dampening the body's ability to burn energy while leaving appetite unaffected.


Teaching an old drug new tricks

Medicine & Health / Medications

created Jan 30, 2009 | popularity 4.5 / 5 (2) | comments 2

A century-old drug that failed in its original intent to treat tuberculosis but has worked well as an antileprosy medicine now holds new promise as a potential therapy for multiple sclerosis and other autoimmune diseases.


Physics, math provide clues to unraveling cancer

Medicine & Health / Cancer

created Jan 30, 2009 | popularity 5 / 5 (7) | comments 5

Biology exists in a physical world. That's a fact cancer researchers are beginning to recognize as they look to include concepts of physics and mathematics in their efforts to understand how cancer develops -- and how to ...


Oncogene inhibits tumor suppressor to promote cancer: Study links B-RAF and LKB1

Medicine & Health / Cancer

created Jan 29, 2009 | popularity not rated yet | comments 0

Scientists have uncovered an interesting connection between two important protein kinase signaling pathways that are associated with cancer. The research, published by Cell Press in the January 30th issue of the journal Molecular Ce ...


Researchers discover 'on switch' for cell death signaling mechanism

Biology /

created Jan 05, 2009 | popularity 4.5 / 5 (6) | comments 0

Scientists at Burnham Institute for Medical Research (Burnham) have determined the structure of the interactions between proteins that form the heart of the death inducing signaling complex (DISC), which is responsible for ...