News tagged with signaling
Crosstalk between critical cell-signaling pathways holds clues to tumor invasion and metastasis
Nov 25, 2009 |
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Two signaling pathways essential to normal human development - the Wnt/Wingless (Wnt) and epidermal growth factor receptor (EGFR) pathways - interact in ways that can promote tumor cell invasion and metastasis, researchers ...
'Cross-talk' mechanism contributes to colorectal cancer
Nov 13, 2009 |
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Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have identified a molecular mechanism that allows two powerful signaling pathways to interact and begin a process leading to colorectal ...
Researchers use drug-radiation combo to eradicate lung cancer
Oct 29, 2009 |
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Researchers at UT Southwestern Medical Center have eliminated non-small cell lung (NSCL) cancer in mice by using an investigative drug called BEZ235 in combination with low-dose radiation.
Wistar researchers show targeting 'normal' cells in tumors slows growth
Nov 16, 2009 |
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Targeting the normal cells that surround cancer cells within and around a tumor is a strategy that could greatly increase the effectiveness of traditional anti-cancer treatments, say researchers at The Wistar Institute.
Study reveals how plants and bacteria 'talk' to thwart disease
Nov 05, 2009 |
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When it comes to plants' innate immunity, like many of the dances of life, it takes two to tango. A receptor molecule in the plant pairs up with a specific molecule on the invading bacteria and, presto, the immune system ...
Research shows why low vitamin D raises heart disease risks in diabetics
Aug 22, 2009 |
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Low levels of vitamin D are known to nearly double the risk of cardiovascular disease in patients with diabetes, and researchers at Washington University School of Medicine in St. Louis now think they know ...
Plants on Steroids: Key Missing Link Discovered
Sep 08, 2009 |
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(PhysOrg.com) -- Researchers at the Carnegie Institution's Department of Plant Biology have discovered a key missing link in the so-called signaling pathway for plant steroid hormones (brassinosteroids). Many important signaling ...
Scientists get detailed glimpse of chemoreceptor architecture in bacterial cells
Sep 24, 2009 |
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Using state-of-the-art electron microscopy techniques, a team led by researchers from Caltech has for the first time visualized and described the precise arrangement of chemoreceptors—the receptors that sense ...
Figuring out the heads or tails decision in regeneration
Sep 14, 2009 |
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Amputations trigger a molecular response that determines if a head or tail will be regrown in planaria, a flatworm commonly studied for its regenerative capabilities. Until now, no molecular connection between wounding and ...
Cannibalistic cells may help prevent infections
Aug 03, 2009 |
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Infectious-disease specialists at UT Southwestern Medical Center have demonstrated that a cannibalistic process in cells plays a key role in limiting Salmonella infection.
What makes stem cells tick?
Aug 06, 2009 |
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Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) ...
Scientists identify roots of diabetic tissue damage
Oct 22, 2009 |
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(PhysOrg.com) -- Results from comprehensive assessments of diabetes' effects on cell metabolism may aid efforts to reduce diabetic damage to nerves, blood vessels and other tissues, according to researchers at Washington ...
Why the thumb of the right hand is on the left hand side
May 22, 2009 |
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It is the concentration of a few signaling molecules that determines the fate of individual cells during the early development of organisms. In the renowned journal Current Biology, a team of molecular biologists led by Pia ...
Fate in fly sensory organ precursor cells could explain human immune disorder
Jun 21, 2009 |
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(June 21, 2009) - Notch signaling helps determine the fate of a number of different cell types in a variety of organisms, including humans. In an article that appears in the current issue of Nature Cell Biology, researchers at Bay ...
Capillary formation’s mechanical determinants: One growth factor can have many effects
Mar 09, 2009 |
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(PhysOrg.com) -- Harvard researchers have established a link between the growth of blood vessels and the mechanical stresses caused by the environment within which the vessels grow, a new understanding that ...


