News tagged with signaling
Why the thumb of the right hand is on the left hand side
May 22, 2009 |
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It is the concentration of a few signaling molecules that determines the fate of individual cells during the early development of organisms. In the renowned journal Current Biology, a team of molecular biologists led by Pia ...
Protein on 'speed' linked to ADHD
Jul 08, 2008 |
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A genetic change in the dopamine transporter – one of the brain's dopamine-handling proteins – makes it behave as if amphetamine is present and "run backward," Vanderbilt University Medical Center investigators report this ...
Study strengthens link between sirtuins proteins and life extension
Dec 14, 2009 |
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(PhysOrg.com) -- A new paper from MIT biology professor Leonard Guarente strengthens the link between longevity proteins called sirtuins and the lifespan-extending effects of calorie restriction.
Physics, math provide clues to unraveling cancer
Jan 30, 2009 |
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Biology exists in a physical world. That's a fact cancer researchers are beginning to recognize as they look to include concepts of physics and mathematics in their efforts to understand how cancer develops -- and how to ...
Plant steroids offer new paradigm for how hormones work
Biology /
Jul 24, 2008 |
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Steroids bulk up plants just as they do human athletes, but the playbook of molecular signals that tell the genes to boost growth and development in plant cells is far more complicated than in human and animal cells. A new ...
Computer model reveals cells' inner workings
Biology /
Oct 16, 2008 |
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(PhysOrg.com) -- After spending years developing a computational model to help illuminate cell signaling pathways, a team of MIT researchers decided to see what would happen if they "broke" the model.
Research shows why low vitamin D raises heart disease risks in diabetics
Aug 22, 2009 |
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Low levels of vitamin D are known to nearly double the risk of cardiovascular disease in patients with diabetes, and researchers at Washington University School of Medicine in St. Louis now think they know ...
Mechanism explains calcium abnormalities in Alzheimer's brain
Jun 25, 2008 |
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A new study uncovers a mechanism that directly links mutations that cause early onset Alzheimer's disease (AD) with aberrant calcium signaling. The research, published by Cell Press in the June 26th issue of the journal Neuron, provid ...
Researchers discover 'on switch' for cell death signaling mechanism
Biology /
Jan 05, 2009 |
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Scientists at Burnham Institute for Medical Research (Burnham) have determined the structure of the interactions between proteins that form the heart of the death inducing signaling complex (DISC), which is responsible for ...
New drug shows promise in the fight against malignant melanoma
Sep 29, 2009 |
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(PhysOrg.com) -- Gavin Robertson is not a man who uses the word ‘hate’ lightly, but he makes no secret of his desire to slay the dragon that is malignant melanoma.
Researchers use drug-radiation combo to eradicate lung cancer
Oct 29, 2009 |
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Researchers at UT Southwestern Medical Center have eliminated non-small cell lung (NSCL) cancer in mice by using an investigative drug called BEZ235 in combination with low-dose radiation.
Discovery of a new signaling mechanism may lead to novel anti-inflammatory therapy
Jul 17, 2008 |
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A team of researchers at the University of California, San Diego School of Medicine has uncovered a new signaling mechanism used to activate protein kinases that are critical for the body's inflammatory response. Their work ...
Calcium may be the key to understanding Alzheimer's disease
Jul 18, 2008 |
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Researchers at the University of Pennsylvania School of Medicine have shown that mutations in two proteins associated with familial Alzheimer's disease disrupt the flow of calcium ions within neurons. The two proteins, called ...
High-fat diets plus extra protein make for bad mix
Apr 07, 2009 |
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It's basically a given that diets loaded with fat can lead to considerable health problems. But a new study in the April issue of Cell Metabolism, a Cell Press publication, shows that in some cases diets that are high in bot ...
Another reason to avoid high-fat diet -- it can disrupt our biological clock
Dec 29, 2008 |
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Indulgence in a high-fat diet can not only lead to overweight because of excessive calorie intake, but also can affect the balance of circadian rhythms - everyone's 24-hour biological clock, Hebrew University of Jerusalem ...
