News tagged with signaling
Crosstalk between critical cell-signaling pathways holds clues to tumor invasion and metastasis
Nov 25, 2009 |
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Two signaling pathways essential to normal human development - the Wnt/Wingless (Wnt) and epidermal growth factor receptor (EGFR) pathways - interact in ways that can promote tumor cell invasion and metastasis, researchers ...
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Brain's endocannabinoid signaling pathway kept in check by two enzymes
Nov 25, 2009 |
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(PhysOrg.com) -- A research team has shown that blocking the degradation of two naturally occurring cannabinoids in the endocannabinoid signaling pathway of the brain produces marijuana-like behavioral effects in mice, according ...
Arsenic biomethylation required for oxidative DNA damage
Nov 23, 2009 |
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Biomethylation of arsenic compounds appears to cause oxidative DNA damage and to increase their carcinogenicity, according to a new study published online November 23 in the Journal of the National Cancer Institute.
Scientists report first effective medical therapy for rare stomach disorder
Nov 25, 2009 |
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A drug used to treat colorectal cancer also can reverse a rare stomach disorder and should be considered first-line therapy for the disease, researchers at Vanderbilt University Medical Center report this week.
Computational microscope peers into the working ribosome (w/ Video)
Nov 23, 2009 |
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Two new studies reveal in unprecedented detail how the ribosome interacts with other molecules to assemble new proteins and guide them toward their destination in biological cells. The studies used molecular ...
Tissue tension regulates tumor progression
Nov 23, 2009 |
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(PhysOrg.com) -- UCSF scientists have shown for the first time that the rigidity of a tissue can induce cancer. The research team identified an enzyme that is crucial for regulating tissue stiffness and demonstrated that ...
Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer
Nov 22, 2009 |
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Agios Pharmaceuticals today announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene. This breakthrough ...
Beyond sunlight: Explorers census 17,650 ocean species between edge of darkness and black abyss (w/ Video)
Nov 22, 2009 |
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Census of Marine Life scientists have inventoried an astonishing abundance, diversity and distribution of deep sea species that have never known sunlight - creatures that somehow manage a living in a frigid ...
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