News tagged with sonic hedgehog
Human ES cells progress slowly in myelin's direction
Apr 09, 2009 |
4.5 / 5 (4) |
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Scientists from the University of Wisconsin, USA, report in the journal Development the successful generation from human embryonic stem cells of a type of cell that can make myelin, a finding that opens up new possibilities for bo ...
Researchers find key to Sonic hedgehog control of brain development
Oct 28, 2008 |
4.4 / 5 (7) |
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University of Pennsylvania School of Medicine researchers have discovered how the expression of the Sonic hedgehog gene is regulated during brain development and how mutations that alter this process cause ...
Researchers Discover Tiny Cellular Antennae Trigger Neural Stem Cells
Biology /
Aug 12, 2008 |
4.8 / 5 (18) |
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(PhysOrg.com) -- Yale University scientists today reported evidence suggesting that the tiny cilia found on brain cells of mammals, thought to be vestiges of a primeval past, actually play a critical role ...
New insight into most common forebrain malformation
Aug 11, 2008 |
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St. Jude Children's Research Hospital scientists have identified one of the molecular mechanisms underlying the genetic brain malformation called holoprosencephaly (HPE). The findings not only yield insights into the most ...
Search results for sonic hedgehog
Sega Puts The Sonic Into Panasonic Mobile Phones
May 20, 2005 |
2.7 / 5 (10) |
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Panasonic today announced that it has secured the rights to feature SEGA’s blockbuster game, Sonic The Hedgehog, on its new series of mobile phones. As previewed on SEGA’s booth at the E3 premier game show ...
Researchers find new molecule to block ‘Hedgehog’ signaling in cancer, development
Biology /
Jan 19, 2009 |
5 / 5 (2) |
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(PhysOrg.com) -- Researchers have achieved a feat drug developers had thought difficult, if not impossible, discovering a compound that blocks the functioning of a key developmental protein by binding to an “undruggable” ...
Mechanism in cells that generate malignant brain tumors may offer target for gene therapy
Oct 24, 2008 |
4.5 / 5 (2) |
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Researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute who first isolated cancer stem cells in adult brain tumors in 2004 have now identified a molecular mechanism that is involved in the development ...
Glypican-3 gene function in regulating body size helps inform novel cancer treatments
May 12, 2008 |
2 / 5 (1) |
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In a leading study that has implications for the development of novel therapies for a number of breast, lung and ovarian cancers that have lost the expression of a gene called glypican-3 (GPC3), Sunnybrook researchers have ...
Researchers discover Hedgehogs could play a role in treating osteoarthritis
Nov 17, 2009 |
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(PhysOrg.com) -- Researchers at the University of Toronto and the Hospital for Sick Children (SickKids) have found a pharmacological approach to treating the disease. The study is published in the November 15 advance online ...
Why the thumb of the right hand is on the left hand side
May 22, 2009 |
4.8 / 5 (13) |
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It is the concentration of a few signaling molecules that determines the fate of individual cells during the early development of organisms. In the renowned journal Current Biology, a team of molecular biologists led by Pia ...
Certain anticancer agents could be harmful to patients with heart disease
Jun 23, 2008 |
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A set of promising new anticancer agents could have unforeseen risks in individuals with heart disease, suggests research at Washington University School of Medicine in St. Louis. The anticancer drugs — which go by the strange ...
'Cross-talk' mechanism contributes to colorectal cancer
Nov 13, 2009 |
5 / 5 (1) |
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Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have identified a molecular mechanism that allows two powerful signaling pathways to interact and begin a process leading to colorectal ...
New Clues to Limb Formation (and Loss) in Some Sea Mammals
Biology /
May 23, 2006 |
5 / 5 (1) |
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Researchers from the Northeastern Ohio Universities College of Medicine have revealed the genetic basis behind one of the best-documented examples of evolutionary change in the fossil record: how whales lost ...
Novel anti-cancer drug yields positive response in people with advanced skin, brain cancer
Sep 02, 2009 |
5 / 5 (1) |
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The Hedgehog signaling pathway is involved in a preliminary study and case report describing positive responses to an experimental anticancer drug in a majority of people with advanced or metastatic basal cell skin cancers. ...
List of search results for sonic hedgehog
