A rare, small RNA turns a gene-splicing machine into a switch that controls the expression of hundreds of human genes. Howard Hughes Medical Institute Investigator and professor of Biochemistry Gideon Dreyfuss, PhD, and his ...
Cell & Microbiology
Aug 21, 2013
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A little-studied factor known as the Little Elongation Complex (LEC) plays a critical and previously unknown role in the transcription of small nuclear RNAs (snRNA), according to a new study led by scientists at the Stowers ...
Cell & Microbiology
Aug 8, 2013
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(Phys.org) —Much of biomedical science – both mystifying and awe-inspiring to the lay public – depends on an unwavering focus on things that can't be easily seen, like the inner-workings of cells, in order to determine ...
Cell & Microbiology
Jul 15, 2013
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When most genes are transcribed, the nascent RNAs they produce are not quite ready to be translated into proteins - they have to be processed first. One of those processes is called splicing, a mechanism by which non-coding ...
Cell & Microbiology
Oct 25, 2010
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Reversing a protein deficiency through gene therapy can correct motor function, restore nerve signals and improve survival in mice that serve as a model for the lethal childhood disorder spinal muscular atrophy, new research ...
Biotechnology
Feb 28, 2010
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