During cell division in a mother cell, the 23 chromosomes that carry the human genome must be first copied and later delivered to two newly forming daughter cells. At least in healthy cells, the result is astonishingly flawless, ...
Molecular & Computational biology
Apr 8, 2022
0
72
For reproduction to be successful, an egg cell must divide perfectly. Egg cell divisions are so error-prone, however, that they are the leading cause of miscarriages and birth defects in humans.
Cell & Microbiology
Mar 29, 2022
0
132
Human eggs often contain the wrong number of chromosomes, leading to miscarriages and infertility. A research team led by Melina Schuh at the Max Planck Institute (MPI) for Multidisciplinary Sciences has discovered that human ...
Cell & Microbiology
Feb 11, 2022
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66
Proper chromosome segregation into two future daughter cells requires the mitotic spindle to elongate in anaphase. However, although some candidate proteins are implicated in this process, the molecular mechanism that drives ...
Cell & Microbiology
Jun 15, 2021
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8
The error-free division of mouse oocytes—the precursors of eggs—needs kinetochores that are rich in a specific microtubule crosslinker, RIKEN researchers have discovered. This finding could explain why the division of ...
Plants & Animals
Jul 31, 2020
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19
An over-abundance of the protein PRC1, which is essential to cell division, is a telltale sign in many cancer types, including prostate, ovarian, and breast cancer. New research, published online today in Developmental Cell, ...
Cell & Microbiology
Jul 7, 2020
0
84
Protein filament systems within cells are subject to constant reorganization, which is in part mediated by the actions of motor proteins. LMU researchers have now shown that motor-driven movements can propagate through such ...
Molecular & Computational biology
Jan 9, 2020
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3
Fleets of microscopic machines toil away in your cells, carrying out critical biological tasks and keeping you alive. By combining theory and experiment, researchers have discovered the surprising way one of these machines, ...
General Physics
Sep 2, 2019
1
477
Researchers at the University of Dundee have solved one of the mysteries of cell division, a discovery which may shed light on cancer development and one day help develop new drugs to treat the disease.
Cell & Microbiology
Jul 31, 2019
0
170
Mitosis is the process by which the genetic information encoded on chromosomes is equally distributed to two daughter cells, a fundamental feature of all life on earth. Scientists led by Alexander Dammermann at the Max Perutz ...
Cell & Microbiology
Jul 11, 2019
0
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