News tagged with splicing factors
Researchers discover a switch that controls stem cell pluripotency
Scientists have found a control switch that regulates stem cell "pluripotency," the capacity of stem cells to develop into any type of cell in the human body. The discovery reveals that pluripotency is regulated by a single ...
Sep 15, 2011 |
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Cancer-associated long non-coding RNA regulates pre-mRNA splicing
Researchers report this month that MALAT1, a long non-coding RNA that is implicated in certain cancers, regulates pre-mRNA splicing - a critical step in the earliest stage of protein production. Their study appears in the ...
Sep 23, 2010 |
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Scientists discover master regulator of motor neuron firing
(PhysOrg.com) -- When the Human Genome Project was complete, DNA bowed out of the limelight and gave way to RNA as a major player in genetic regulation. Now, findings at Rockefeller University mirror this ...
Medicine & Health / Neuroscience
Mar 16, 2009 |
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Something old, something new: Evolution and the structural divergence of duplicate genes
(PhysOrg.com) -- Gene duplications are arguably the driving force of organismal evolution and if they survive, such duplicate genes will diverge in both regulatory and coding genomic regions. Coding ...
Bugs may be resistant to genetically modified corn
(AP) -- One of the nation's most widely planted crops - a genetically engineered corn plant that makes its own insecticide - may be losing its effectiveness because a major pest appears to be developing resistance ...
Dec 29, 2011 |
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Scientists discover new way to target cancer
Scientists have discovered a new way to target cancer through manipulating a master switch responsible for cancer cell growth.
Dec 12, 2011 |
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Massive DNA search uncovers new mutations driving blood cancer
The most comprehensive search to date of DNA abnormalities in chronic lymphocytic leukemia (CLL) has unearthed several new altered genes that drive this common blood cancer, a finding that could potentially ...
Dec 12, 2011 |
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Keeping stress at a distance
Beep-beep, tick, shoosh, beep-beep, tick, shoosh. Four tiny incisions are made in the patients abdomen thin metal tools are inserted into the incisions.
Nov 18, 2011 |
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The rate of data transmission over plastic optical fibers can be increased by controlling modal dispersion
Plastic optical fibers offer a more efficient method of data transmission in telecommunications. While glass optical fibers allow very high data rates to be transmitted, they are expensive and difficult to ...
Oct 28, 2011 |
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Long-term correction of severe spinal muscular atrophy by antisense therapy
A new study from Cold Spring Harbor Laboratory (CSHL) reports surprising results that suggest that the devastating neuromuscular disease, spinal muscular atrophy (SMA), might not exclusively affect the motor neurons in the ...
Oct 05, 2011 |
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New mechanism in the regulation of human genes
Scientists at the Technical University of Munich and the Helmholtz Zentrum Muenchen and along with their colleagues from the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Centre for Genomic Regulation ...
Jul 14, 2011 |
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Safeguarding genome integrity through extraordinary DNA repair
(PhysOrg.com) -- DNA is under constant attack, from internal factors like free radicals and external ones like ionizing radiation. About 10 double-strand breaks the kind that snap both backbones of ...
Apr 19, 2011 |
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'SKIP'-ing splicing forces tumor cells to undergo programmed cell death
When cells find themselves in a tight spot, the cell cycle regulator p21 halts the cell cycle, buying cells time to repair the damage, or if all else fails, to initiate programmed cell death. In contrast to other stress-induced ...
Apr 01, 2011 |
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List of search results for splicing factors