News tagged with splicing
Possible help in fight against muscle-wasting disease (w/ Video)
Nov 06, 2009 |
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(PhysOrg.com) -- A compound already used to treat pneumonia could become a new therapy for an inherited muscular wasting disease, according to researchers at the University of Oregon and the University of ...
Researchers identify drug candidate for treating spinal muscular atrophy
Nov 04, 2009 |
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A chemical cousin of the common antibiotic tetracycline might be useful in treating spinal muscular atrophy (SMA), a currently incurable disease that is the leading genetic cause of death in infants. This is the finding of ...
Of yeast and men: Unraveling the molecular mechanisms of Friedreich's ataxia
Jul 09, 2009 |
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Researchers in human genetics have long known that expansions of GAA repeats - resulting in this nucleotide triplet repeating hundreds or thousands of times - cause the most common hereditary neurological disorder known as ...
Getting more from whole-transcript microarrays
May 21, 2009 |
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The widely-used Affymetrix Whole-Transcript Gene 1.0 ST (sense target) microarray platform, normally used to assay gene expression, can also be utilized to interrogate exon-specific splicing. Research published today in the ...
Scientists discover master regulator of motor neuron firing
Medicine & Health / Neuroscience
Mar 16, 2009 |
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(PhysOrg.com) -- When the Human Genome Project was complete, DNA bowed out of the limelight and gave way to RNA as a major player in genetic regulation. Now, findings at Rockefeller University mirror this ...
Siestas Among the Drosophilae
Biology /
Jan 28, 2009 |
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(PhysOrg.com) -- Isaac Edery is concerned with biological clocks, internal mechanisms that enable virtually all plants and animals to behave in rhythmic biological cycles known as circadian rhythms.
Scientists clarify editing error underlying genetic neurodegenerative disease
Biology /
Jan 28, 2009 |
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Two molecular biologists at Cold Spring Harbor Laboratory have uncovered important new details about how a gene mutation causes a cellular editing error that results in a devastating disease called pontocerebellar hypoplasia ...
Researchers find mechanism underlying alt. splicing of premessenger RNA into messenger RNA
Biology /
Dec 24, 2008 |
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An international research team led by Tim Nilsen, Ph.D., a professor of medicine and biochemistry and the director of the School of Medicine's Center for RNA Molecular Biology, has discovered an unexpected mechanism governing ...
Gene Expression and Splicing Vary Widely from One Tissue to the Next
Biology /
Dec 23, 2008 |
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(PhysOrg.com) -- Genes talk to themselves and to each other to control how a given cell manufactures proteins. But variation in the control of the same gene in two different tissues may contribute to certain human traits, ...
Alternative splicing proteins prompt heart development
Dec 08, 2008 |
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Just as the emotions it represents are dynamic, the heart's development requires dynamic shifts in proteins that prompt alternative spicing, a mechanism that allows a given gene to program the cell to make several proteins, ...
Scientists trace extensive networks regulating alternative RNA splicing
Biology /
Sep 20, 2008 |
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[B]RNA targets of tissue-specific splicing factors Fox-1 and Fox-2 are successfully predicted[/B] Two professors at Cold Spring Harbor Laboratory (CSHL) have succeeded in tracing intricate biochemical networks involving a c ...
Deep sequencing study reveals new insights into human transcriptome
Biology /
Jul 08, 2008 |
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In a collaborative project scientists from the Max-Planck-Institute for Molecular Genetics in Berlin (MPI MolGen), Germany and Genomatix with a business in Munich, Germany and Ann Arbor, MI, USA, applied next generation sequencing ...
