Related topics: embryonic stem cells , cells , proceedings of the national academy of sciences , barack obama , bone marrow
Stem cell
hideStem cells are cells found in most, if not all, multi-cellular organisms. They are characterized by the ability to renew themselves through mitotic cell division and differentiating into a diverse range of specialized cell types. Research in the stem cell field grew out of findings by Canadian scientists Ernest A. McCulloch and James E. Till in the 1960s. The two broad types of mammalian stem cells are: embryonic stem cells that are isolated from the inner cell mass of blastocysts, and adult stem cells that are found in adult tissues. In a developing embryo, stem cells can differentiate into all of the specialized embryonic tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialized cells, but also maintain the normal turnover of regenerative organs, such as blood, skin or intestinal tissues.
Stem cells can now be grown and transformed into specialized cells with characteristics consistent with cells of various tissues such as muscles or nerves through cell culture. Highly plastic adult stem cells from a variety of sources, including umbilical cord blood and bone marrow, are routinely used in medical therapies. Embryonic cell lines and autologous embryonic stem cells generated through therapeutic cloning have also been proposed as promising candidates for future therapies.
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News tagged with stem cells
When is a stem cell really a stem cell?
Nov 24, 2009 |
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(PhysOrg.com) -- Induced pluripotent stem (iPS) cells -- adult cells reprogrammed to look and function like versatile embryonic stem cells -- are of growing interest in medicine. They may provide a way to ...
New discovery about the formation of new brain cells
Nov 23, 2009 |
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The generation of new nerve cells in the brain is regulated by a peptide known as C3a, which directly affects the stem cells' maturation into nerve cells and is also important for the migration of new nerve cells through ...
New research shows versatility of amniotic fluid stem cells
Nov 23, 2009 |
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For the first time, scientists have demonstrated that stem cells found in amniotic fluid meet an important test of potential to become specialized cell types, which suggests they may be useful for treating a wider array of ...
Gene mismatch influences success of bone marrow transplants
Nov 22, 2009 |
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A commonly inherited gene deletion can increase the likelihood of immune complications following bone marrow transplantation, an international team of researchers reports in the November 22 advance online issue of Nature Ge ...
First reconstitution of an epidermis from human embryonic stem cells
Nov 20, 2009 |
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Stem cell research is making great strides. This is yet again illustrated by a study carried out by the I-STEM Institute (France), published in the Lancet on 21 November 2009. The I-STEM team, directed by Marc Peschanski has su ...
Bone Implant Offers Hope for Skull Deformities
Nov 19, 2009 |
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(PhysOrg.com) -- A synthetic bone matrix offers hope for babies born with craniosynostosis, a condition that causes the plates in the skull to fuse too soon. Implants replacing some of the infant’s bone with the biodegradable ...
Embryonic stem cell therapy closer to human trials
Nov 19, 2009 |
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Embryonic stem cell therapy got a step closer to the clinic Thursday after US researchers said they filed a request for government approval of human trials.
Beyond genomics, biologists and engineers decode the next frontier
Nov 18, 2009 |
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(PhysOrg.com) -- A team of Princeton biologists and engineers has dramatically improved the speed and accuracy of measuring an enigmatic set of proteins that influences almost every aspect of how cells and ...
Is hepatic differentiation of embryonic stem cells induced by valproic acid and cytokines?
Nov 18, 2009 |
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Embryonic stem (ES) cells, known for their capacity to proliferate indefinitely and differentiate into almost all types of cells including hepatocytes, have raised the hope of cellular replacement therapy for liver failure. ...
Your own stem cells can treat heart disease
Nov 17, 2009 |
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The largest national stem cell study for heart disease showed the first evidence that transplanting a potent form of adult stem cells into the heart muscle of subjects with severe angina results in less pain and an improved ...
Stem cells alleviate tumor treatment side effects
Nov 17, 2009 |
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(PhysOrg.com) -- Human embryonic stem cells could help people with learning and memory deficits after radiation treatment for brain tumors, suggests a new UC Irvine study.
On your last nerve: Researchers advance understanding of stem cells
Nov 17, 2009 |
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Researchers from North Carolina State University have identified a gene that tells embryonic stem cells in the brain when to stop producing nerve cells called neurons. The research is a significant advance ...
The indefinite self-renewal of specialized cells without the need for stem cell intermediates
Nov 16, 2009 |
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(PhysOrg.com) -- Is the indefinite expansion of adult cells possible without recourse to stem cell intermediates? The team led by Michael Sieweke at the Centre d'immunologie de Marseille Luminy, France has ...
Protecting the future: How plant stem cells guard against genetic damage
Nov 16, 2009 |
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Scientists at the John Innes Centre in Norwich, UK, have shown how plants can protect themselves against genetic damage caused by environmental stresses. The growing tips of plant roots and shoots have an ...
Investigating muscle repair, scientists follow their noses
Nov 16, 2009 |
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When muscle cells need repair, they use odor-detecting tools found in the nose to start the process, researchers have discovered.
