Related topics: embryonic stem cells , cells , bone marrow , pluripotent stem cells , skin cells
Stem cell
hideStem cells are cells found in most, if not all, multi-cellular organisms. They are characterized by the ability to renew themselves through mitotic cell division and differentiating into a diverse range of specialized cell types. Research in the stem cell field grew out of findings by Canadian scientists Ernest A. McCulloch and James E. Till in the 1960s. The two broad types of mammalian stem cells are: embryonic stem cells that are isolated from the inner cell mass of blastocysts, and adult stem cells that are found in adult tissues. In a developing embryo, stem cells can differentiate into all of the specialized embryonic tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialized cells, but also maintain the normal turnover of regenerative organs, such as blood, skin or intestinal tissues.
Stem cells can now be grown and transformed into specialized cells with characteristics consistent with cells of various tissues such as muscles or nerves through cell culture. Highly plastic adult stem cells from a variety of sources, including umbilical cord blood and bone marrow, are routinely used in medical therapies. Embryonic cell lines and autologous embryonic stem cells generated through therapeutic cloning have also been proposed as promising candidates for future therapies.
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News tagged with stem cells
Researchers demonstrate that stem cells can be engineered to kill HIV
Medicine & Health / HIV & AIDS
Dec 08, 2009 |
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(PhysOrg.com) -- UCLA AIDS Institute researchers have for the first time demonstrated that human blood stem cells can be engineered to target and kill HIV-infected cells.
When is a stem cell really a stem cell?
Nov 24, 2009 |
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(PhysOrg.com) -- Induced pluripotent stem (iPS) cells -- adult cells reprogrammed to look and function like versatile embryonic stem cells -- are of growing interest in medicine. They may provide a way to ...
Study reveals lack of diversity in embryonic stem cell lines
Dec 16, 2009 |
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The most widely used human embryonic stem cell lines lack genetic diversity, a finding that raises social justice questions that must be addressed to ensure that all sectors of society benefit from stem cell advances, according ...
Stem-cell activators switch function, repress mature cells
Dec 16, 2009 |
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In a developing animal, stem cells proliferate and differentiate to form the organs needed for life. A new study shows how a crucial step in this process happens and how a reversal of that step contributes to cancer.
Marking of tissue-specific crucial in embryonic stem cells to ensure proper function
Dec 16, 2009 |
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Tissue-specific genes, thought to be dormant or not marked for activation in embryonic stem cells, are indeed marked by transcription factors, with proper marking potentially crucial for the function of tissues derived from ...
Researchers find reproductive germ cells survive and thrive in transplants, even among species
Dec 15, 2009 |
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Reproductive researchers from the University of Pennsylvania and The Children's Hospital of Philadelphia have succeeded in isolating and transplanting pure populations of the immature cells that enable male ...
Newly discovered mechanism allows cells to change state
Dec 09, 2009 |
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Cells are not static. They can transform themselves over time — but change can have dangerous implications. Benign cells, for example, can suddenly change into cancerous ones.
Researchers identify new stem cell
Dec 07, 2009 |
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(PhysOrg.com) -- Scientists have discovered a new type of stem cell in the skin that acts surprisingly like certain stem cells found in embryos: both can generate fat, bone, cartilage, and even nerve cells. These newly-described ...
Stem cells battle for space
Dec 04, 2009 |
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The body is a battle zone. Cells constantly compete with one another for space and dominance. Though the manner in which some cells win this competition is well known to be the survival of the fittest, how stem cells duke ...
Potential new 'twist' in breast cancer detection
Dec 04, 2009 |
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Working with mice, scientists at Johns Hopkins publishing in the December issue of Neoplasia have shown that a protein made by a gene called "Twist" may be the proverbial red flag that can accurately distinguish stem cells ...
Study suggests adult stem cells may help repair hearts damaged by heart attack
Dec 02, 2009 |
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Adult stem cells may help repair heart tissue damaged by heart attack according to the findings of a new study to be published in the December 8 issue of the Journal of the American College of Cardiology. Results from t ...
New stem cell lines approved for tax-paid research
Dec 02, 2009 |
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(AP) -- Scientists can start using taxpayer dollars to do research with 13 batches of embryonic stem cells and the government says dozens more cell lines should be available soon, opening a new era for the potentially life-saving ...
Discovery makes brain tumor cells more responsive to radiation
Dec 02, 2009 |
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Duke University Medical Center researchers have figured out how stem cells in the malignant brain cancer glioma may be better able to resist radiation therapy. And using a drug to block a particular signaling pathway in these ...
Brown fat cells make 'spare tires' shrink
Dec 01, 2009 |
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(PhysOrg.com) -- Scientists at the University of Bonn have found a new signalling pathway which stimulates the production and function of so-called brown fat cells. They propose using these cells that serve as a "natural ...
New discovery about the formation of new brain cells
Nov 23, 2009 |
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The generation of new nerve cells in the brain is regulated by a peptide known as C3a, which directly affects the stem cells' maturation into nerve cells and is also important for the migration of new nerve cells through ...
