Every day, our cells are hard at work multiplying. Cell division is a precise process, but sometimes this process is impaired and diseases like cancer occur. Mitosis is one of the most important phases in the cell cycle. ...
Cell & Microbiology
Mar 28, 2024
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15
The tumor suppressor protein p53 has been dubbed the "guardian of the genome" because it protects the DNA from stress or long-term damage by regulating the expression of numerous genes involved DNA repair, cell division and ...
Molecular & Computational biology
Jun 30, 2023
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50
There is a tightly regulated balance between cell growth and death in healthy tissue. The loss of this balance is essentially what initiates cancer.
Cell & Microbiology
Oct 19, 2022
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2
Often called the building blocks of life, cells are complex and highly dynamic. The genetic information encoded inside enables them to build biomolecular components like proteins, DNA, and RNA, which assemble into larger, ...
Biochemistry
Jan 28, 2021
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12
Geneticist Jolanda van Leeuwen remembers the day she made a striking observation that would take her down a new research path. A strain of yeast cells carrying a complete deletion of an essential gene in their genomes, which ...
Cell & Microbiology
Sep 30, 2020
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20
The gene p53 is extremely important in cell biology and, hence, the world of cell replacement therapy. Its role is to regulate the cell cycle and halt the formation of tumors, leading to its nickname the "tumor suppressor ...
Cell & Microbiology
Jun 1, 2020
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1
The more than 200 different types of human cells have the same DNA but express different ensembles of genes. Each cell type was derived from embryonic stem cells, which are called pluripotent stem cells because they can differentiate ...
Cell & Microbiology
Nov 15, 2017
0
97
For several years, scientists have known that SIRT6 – one of seven sirtuins, a family of mammalian proteins with important biological functions, including promoting longer, healthier life – is a tumor suppressor. It has ...
Biochemistry
May 11, 2017
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4
Northwestern Medicine scientists have revealed the role amino-terminal methylation plays in a specific protein in the centromere, a region of the chromosome important in cell division, and how the dysregulation of this protein ...
Biochemistry
Apr 19, 2017
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9
Two studies publishing on 1st September in Open Access journal PLOS Biology identify overlapping groups of cells in the Drosophila larva that have unique properties. In one case, the cells are resistant to irradiation or ...
Cell & Microbiology
Sep 1, 2016
0
8
