News tagged with suppressor genes
New tumor suppressor gene identified
A recent study published in Clinical Cancer Research suggests that the protein hVps37A suppresses tumor growth in ovarian cancer. The work, which was funded by the Austrian Science Fund FWF, shows, for th ...
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New research sheds light on gene destruction linked to aggressive prostate cancer
Researchers at Queen's University in Kingston, Canada have identified a possible cause for the loss of a tumour suppressor gene (known as PTEN) that can lead to the development of more aggressive forms of prostate cancer.
Jan 26, 2012 |
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Women with certain type of ovarian cancer and BRCA gene mutation have improved survival at 5 years
Among women with invasive epithelial ovarian cancer, patients having a germline (gene change in a reproductive cell that could be passed to offspring) mutation in the BRCA1 or BRCA2 genes was associated with improved 5-year ...
Jan 24, 2012 |
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Why cholesterol-lowering statins might treat cancer
Cholesterol-lowering statins seem to keep breast cancer at bay in some patients. Now researchers reporting in the January 20th issue of the journal Cell, a Cell Press publication, provide clues about how statins might yield ...
Jan 19, 2012 |
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Cleveland Clinic researcher discovers genetic cause of thyroid cancer
Cleveland Clinic researchers have discovered three genes that increase the risk of thyroid cancer, which is has the largest incidence increase in cancers among both men and women.
Dec 23, 2011 |
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Fish oil may hold key to leukemia cure
A compound produced from fish oil that appears to target leukemia stem cells could lead to a cure for the disease, according to Penn State researchers. The compound -- delta-12-protaglandin J3, or D12-PGJ3 ...
Dec 22, 2011 |
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ORNL image analysis prowess advances retina research
Armed with a new ability to find retinal anomalies at the cellular level, neurobiologists at St. Jude Children's Research Hospital have made a discovery they hope will ultimately lead to a treatment for cancer of the retina.
Dec 21, 2011 |
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SABCS: Loss of RB in triple negative breast cancer associated with favorable clinical outcome
Researchers at the Thomas Jefferson University Hospital and Kimmel Cancer Center at Jefferson have shown that loss of the retinoblastoma tumor suppressor gene (RB) in triple negative breast cancer patients is associated with ...
Dec 09, 2011 |
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Proteins do not predict outcome of herceptin treatment in HER2-positive breast cancer
Precisely quantifying the amount of three different HER growth proteins, along with several other proteins believed linked to breast cancer, did not predict a patient's outcome after treatment for HER2-Positive Breast Cancer ...
Dec 09, 2011 |
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From genomic data to new cancer drug
New discoveries about follicular lymphoma, a currently intractable form of cancer, highlight the power of functional genomics in cancer gene discovery. A report in the Oct 28th issue of Cell demonstrates how genetic insigh ...
Oct 27, 2011 |
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HPV linked to cardiovascular disease in women
Women with cancer-causing strains of human papillomavirus (HPV) may be at increased risk for cardiovascular disease (CVD) and stroke even when no conventional risk factors for CVD are present.
Medicine & Health / Cardiology
Oct 24, 2011 |
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Feed a cold -- starve a tumor
The condition tuberous sclerosis, due to mutation in one of two tumor suppressor genes, TSC1 or TSC2, causes the growth of non-malignant tumors throughout the body and skin. These tumors can be unsightly and cause serious ...
Oct 21, 2011 |
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Researchers discover hidden genetic influence on cancer
In findings with major implications for the genetics of cancer and human health, researchers at Beth Israel Deaconess Medical Center (BIDMC) and two other science teams in New York City and Rome have uncovered evidence of ...
Oct 13, 2011 |
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Researchers identify potential molecular target to prevent growth of cancer cells
Researchers have shown for the first time that the protein fortilin promotes growth of cancer cells by binding to and rendering inert protein p53, a known tumor suppressor. This finding by researchers at the University of ...
Sep 16, 2011 |
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Small molecules shed light on cancer therapies
Patients suffering from an aggressive brain cancer will benefit from the results of a University of Illinois study that could advance the development of targeted gene therapies and improve prognosis.
Aug 22, 2011 |
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