T cell
hideT cells belong to a group of white blood cells known as lymphocytes, and play a central role in cell-mediated immunity. They can be distinguished from other lymphocyte types, such as B cells and natural killer cells by the presence of a special receptor on their cell surface called T cell receptors (TCR). The abbreviation T, in T cell, stands for thymus, since this is the principal organ responsible for the T cell's maturation. Several different subsets of T cells have been discovered, each with a distinct function.
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News tagged with t cell
Study reveals a 'missing link' in immune response to disease (w/ Video)
Nov 02, 2009 |
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The immune system's T cells have the unique responsibilities of being both jury and executioner. They examine other cells for signs of disease, including cancers or infections, and, if such evidence is found, ...
ID3 provides career counseling for blood progenitors, driving the creation of gamma-delta T cells
Oct 15, 2009 |
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Like an unusually forceful career counselor, the Id3 protein decides the fate of a given white blood cell precursor, according to researchers at Fox Chase Cancer Center. Their findings, published today in the journal Immunity, de ...
New Cellular Therapy for HIV in World's First Engineered T Cell Receptor Trial
Medicine & Health / HIV & AIDS
Oct 07, 2009 |
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(PhysOrg.com) -- Researchers at Adaptimmune Limited and the University of Pennsylvania School of Medicine, today announced the approval of an Investigational New Drug (IND) application from the US Food and ...
Drug That Crosses Blood-Brain Barrier Reduces Formation of Brain Metastases in Mice
Sep 29, 2009 |
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(PhysOrg.com) -- The drug vorinostat is able to cross the blood-brain barrier and reduce the development of large metastatic tumors in mice brains by 62 percent when compared to mice that did not receive the drug, according ...
The difficult Way to HIV Vaccine
Medicine & Health / HIV & AIDS
Sep 16, 2009 |
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T cells are key players in the immune response to HIV, which are able to delete infected cells. This capacity is used for vaccine development against HIV. “To date however, success of this strategy remains elusive. Our understanding ...
Engineered human fusion protein inhibits HIV-1 replication
Sep 08, 2009 |
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In 2004, Jeremy Luban and colleagues from the University of Geneva, Switzerland, reported that New World owl monkeys (Aotus genus) make a fusion protein - AoT5Cyp - that potently blocks HIV-1 infection. The human genome encodes ...
Got zinc? New zinc research suggests novel therapeutic targets
Jul 30, 2009 |
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Everyone knows that vitamins "from A to zinc" are important for good health. Now, a new research study in the August 2009 print issue of the Journal of Leukocyte Biology suggests that zinc may be pointing the way to new th ...
Bcl6 gene sculpts helper T cell to boost antibody production
Jul 23, 2009 |
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Expression of a single gene programs an immune system helper T cell that fuels rapid growth and diversification of antibodies in a cellular structure implicated in autoimmune diseases and development of B cell lymphoma, scientists ...
Study may explain why HIV progresses faster in women than in men with same viral load
Medicine & Health / HIV & AIDS
Jul 13, 2009 |
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One of the continuing mysteries of the HIV/AIDS epidemic is why women usually develop lower viral levels than men following acute HIV-1 infection but progress faster to AIDS than men with similar viral loads. Now a research ...
Starting antiretroviral therapy earlier yields better clinical outcomes
Medicine & Health / HIV & AIDS
Jun 09, 2009 |
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A clinical trial has demonstrated that HIV-infected adults in a resource-limited setting are more likely to survive if they start antiretroviral therapy (ART) before their immune systems are severely compromised.
Process controlling T cell growth and production identified
May 03, 2009 |
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Identifying one of the processes that plays a role in naďve and memory T-cells' growth and production could one day lead to better vaccines and possibly more effective cancer immunotherapy, said researchers at Baylor ...
Researchers Formulate Treatment Combination Lethal To Pancreatic Cancer Cells (w/Video)
Apr 20, 2009 |
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A combination of two targeted therapies packs a powerful punch to kill pancreatic cancer cells in the laboratory, Mayo Clinic cancer researchers report. With further testing of these drugs that are from classes of pharmaceuticals ...
Dendritic cells ensure immune tolerance
Mar 16, 2009 |
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Dendritic cells are essential to the body's immune defenses. Now, Ludwig-Maximilians-Universitaet Muenchen (Germany) researchers show that they also have to protect the body from itself: They help to identify any immune cells ...
Discovery may lead to development of safer immunosuppressants
Mar 12, 2009 |
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Immunosuppressive treatment is necessary to prevent rejection of an organ after transplant and has great potential for treating chronic inflammatory diseases. However, currently available immunosuppressant drugs can pose ...
Liver transplant recipients with hepatitis B may need lifelong antiviral treatment
Feb 26, 2009 |
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Patients who undergo liver transplantation for hepatitis B-related liver damage should receive lifelong antiviral treatment to keep the disease from coming back. A new study shows that they lack cellular immunity against ...
