Oseltamivir
hideOseltamivir (INN) (pronounced /ɒsəlˈtæmɨvɪr/) is a drug that blocks the influenza virus from spreading between cells in the body. Thus it is an antiviral drug that is used in the treatment and prophylaxis of both Influenzavirus A and Influenzavirus B infection. Like zanamivir, oseltamivir is a neuraminidase inhibitor. It acts as a transition-state analogue inhibitor of influenza neuraminidase, preventing progeny virions from detaching from infected cells.
Oseltamivir was the first orally active neuraminidase inhibitor commercially developed. It is a prodrug, which is hydrolysed hepatically to the active metabolite, the free carboxylate of oseltamivir (GS4071). It was developed by US-based Gilead Sciences and is currently marketed by Hoffmann–La Roche (Roche) under the trade name Tamiflu. In Japan, it is marketed by Chugai Pharmaceutical Co., which is more than 50% owned by Roche. Oseltamivir is generally available by prescription only.
Roche estimates that 50 million people have been treated with oseltamivir. The majority of these have been in Japan, where an estimated 35 million have been treated. Since June 2009, Roche has been forced to allow other companies to develop competing drugs to Tamiflu, after much speculation about Roche's so-called 'monopoly' of Tamiflu in the UK.[citation needed]
For more information about Oseltamivir, read the full article at
Wikipedia.
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News tagged with tamiflu
Swine flu vaccine effective despite mutations: experts
19 hours ago |
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Swine flu vaccines are still effective despite reported cases of mutations in the A(H1N1) virus, health experts in Europe and North America said Saturday.
Tamiflu-resistant swine flu cluster reported in NC
Nov 20, 2009 |
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(AP) -- Four North Carolina patients at a single hospital tested positive for a type of swine flu that is resistant to Tamiflu, health officials said Friday. The cases reported at Duke University Medical Center over six ...
Ukraine calls for help fighting swine flue
Nov 01, 2009 |
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Ukraine made an urgent appeal to world powers for help battling swine flu on Sunday, after 60 people died from respiratory problems in a week.
CDC: Up to 6 million swine flu cases in few months
Oct 29, 2009 |
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(AP) -- As many as 5.7 million Americans were infected with swine flu during the first few months of the pandemic, according to estimates from federal health officials.
Study: Cholesterol drugs may improve flu survival
Medicine & Health / Medications
Oct 29, 2009 |
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(AP) -- A new treatment for swine flu may already be on pharmacy shelves - cholesterol-lowering statin drugs like Lipitor and Zocor.
FDA warns: Swine flu scams lurk on the Internet
Medicine & Health / Medications
Oct 22, 2009 |
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(AP) -- Air "sterilizers." A photon machine. Supplement pills to boost the immune system. Protective shampoos and face masks. Even fake Tamiflu.
Tamiflu Metabolite Found in Sewage Discharge, River Water
Oct 01, 2009 |
4.3 / 5 (3) |
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(PhysOrg.com) -- In a study published September 28th ahead of print in the peer-reviewed journal Environmental Health Perspectives, researchers measured oseltamivir carboxylate (OC), the active metabolite of the popular anti-i ...
CDC: 25 cities and states order swine flu vaccine
Medicine & Health / Medications
Oct 01, 2009 |
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(AP) -- Twenty-five cities and states have ordered swine flu vaccine, and the first doses should be administered Tuesday, officials said Thursday.
McTriage: Hospitals use drive-thrus for swine flu
Sep 29, 2009 |
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(AP) -- Fast-food places have them. Banks and pharmacies do, too. Now hospitals are opening drive-thrus and drive-up tent clinics to screen and treat a swelling tide of swine flu patients.
Drugmaker reports shortage of kids' Tamiflu
Medicine & Health / Medications
Sep 23, 2009 |
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(AP) -- The maker of Tamiflu on Wednesday said there's a shortage of the children's version of the drug - the first-line treatment for swine flu and seasonal flu.
Study: New drug fights flu as well as Tamiflu does
Medicine & Health / Medications
Sep 13, 2009 |
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(AP) -- A new flu medicine may be on the way. Researchers say the experimental drug peramivir (purr-AM-uh-veer) works as well as Tamiflu for clearing up flu symptoms.
Did drug-resistant swine flu spread at NC camp?
Sep 10, 2009 |
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(AP) -- Health officials are reporting what may be the first instance of a Tamiflu-resistant swine flu virus spreading from one person to another.
US says Tamiflu for the sick, not a preventive
Medicine & Health / Medications
Sep 08, 2009 |
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(AP) -- Federal health officials put out new guidelines Tuesday that say the flu medicines Tamiflu and Relenza should only be used to treat people who are sick with the flu and at high risk for complications.
Swine flu rises at US colleges as students return
Aug 28, 2009 |
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(AP) -- Georgia Tech freshman Elise Woodall was met with a message scrawled on the bathroom mirror of her dorm when she moved in two weeks ago: "Wash your hands. Swine is not fine."
WHO: Save Tamiflu for the young, old and pregnant
Medicine & Health / Medications
Aug 22, 2009 |
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(AP) -- The World Health Organization said Friday that Tamiflu should only be given to particularly vulnerable people - a warning to countries like Britain where the swine flu drug is being handed out freely.
