News tagged with tamoxifen resistance
'New' estrogen receptor found to be key player in tamoxifen resistance
Oct 30, 2008 |
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Researchers at Georgetown University Medical Center have discovered a novel way in which breast cancer cells become resistant to tamoxifen, the world's largest-selling breast cancer prevention and treatment drug. They say ...
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Further breakthroughs for breast cancer patients
Jan 18, 2008 |
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Researchers at the Tenovus Centre for Cancer Research at Cardiff University have made a breakthrough in breast cancer treatment that could help save the lives of women who become resistant to breast cancer drugs such as tamoxifen.
Unsuspected protein determines resistance to breast cancer treatment
Feb 04, 2008 |
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An innovative research approach has identified a previously unsuspected protein as a key player in the resistance to particular forms of breast cancer therapy. The study, published by Cell Press in the February issue of Cancer Ce ...
New cause of Tamoxifen resistance is found
Aug 13, 2007 |
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U.S. scientists have discovered a new mechanism for resistance to Tamoxifen and Faslodex endocrine or anti-hormonal breast cancer therapies.
Cholesterol appears to promote tamoxifen resistance in some breast cancer cells
Apr 20, 2009 |
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Breast cancer cells in the laboratory that don't respond to tamoxifen may be producing high amounts of cholesterol in order to provide a kind of shield against the drug, say researchers at Georgetown University Medical Center ...
Estrogen receptor-alpha, breast cancer patients and tamoxifen response
Nov 25, 2009 |
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Researchers have found evidence of a statistically significant survival benefit from adjuvant tamoxifen among patients whose estrogen receptor (ER)-positive tumors had high levels of phosphorylation of ER-alpha; at serine-118 ...
A new take on growth factor signaling in tamoxifen resistance
Jun 24, 2009 |
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Differences in growth factor (GF) signaling may cause the poor prognosis in some breast cancer cases. A new study, published in the open access journal BMC Medical Genomics, suggests that some estrogen receptor-positive breast ...
Calculating how breast cancers will respond to tamoxifen
Sep 08, 2008 |
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A discovery by Australian scientists could help clinicians decide which women with breast cancer will make good candidates for anti-oestrogen therapies, such as tamoxifen, and which will not.
Genetic variation of enzyme linked with outcomes for women receiving tamoxifen
Oct 06, 2009 |
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Among women with early stage breast cancer, genetic variation of a certain enzyme appears to be associated with clinical outcomes for women treated with tamoxifen, according to a study in the October 7 issue of JAMA.
Breast cancer survival rates improved by novel drug sequence, say researchers
Feb 13, 2007 |
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Changing the way women are treated for breast cancer could improve their overall chance of survival, according to research published today in the Lancet. The new paper shows that switching to a drug called exemestane, two to ...
Researchers develop new method for breast cancer biomarker discovery
Jun 09, 2009 |
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Three researchers from the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed and evaluated a new one-step bioanalytical approach that allows them to profile in detail complex cellular extracts of proteins. ...
List of search results for tamoxifen resistance
