News tagged with tangles
Untangling the mysteries of Alzheimer's
One of the most distinctive signs of the development of Alzheimer's disease is a change in the behavior of a protein that neuroscientists call tau. In normal brains, tau is present in individual units essential to neuron ...
Medicine & Health / Neuroscience
Feb 02, 2012 |
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Alzheimer's: French scientists focus on key target
French scientists said on Tuesday that lack of a key brain protein was linked to Alzheimer's, a finding that threw up a tempting target for drugs to fight the disease.
Medicine & Health / Neuroscience
Jan 24, 2012 |
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Characterizing a toxic offender
The brains of individuals with Alzheimer's disease contain protein aggregates called plaques and tangles, which interfere with normal communication between nerve cells and cause progressive learning and memory ...
Medicine & Health / Neuroscience
Dec 09, 2011 |
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Imaging technique IDs plaques, tangles in brains of severely depressed older adults
Depression is one of the most common mental disorders in the elderly, but little is known about the underlying biology of its development in older adults.
Medicine & Health / Psychology & Psychiatry
Nov 08, 2011 |
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Chemical engineers help decipher mystery of neurofibrillary tangle formation in Alzheimer's brains
Neurofibrillary tangles – odd, twisted clumps of protein found within nerve cells – are a pathological hallmark of Alzheimer's disease. The tangles, which were first identified in the early 1900s by German psychiatrist ...
Nov 02, 2011 |
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The tangled web in Alzheimer's protein deposits is more complex than once thought
Scientists from the National Institutes of Health in the United States have made an important discovery that should forever change the scope and direction of Alzheimer's research. Specifically, they have discovered that the ...
Medicine & Health / Neuroscience
Nov 01, 2011 |
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Single traumatic brain injury may prompt long-term neurodegeneration
Years after a single traumatic brain injury (TBI), survivors still show changes in their brains. In a new study, researchers from the Perelman School of Medicine at the University of Pennsylvania suggest that Alzheimer's ...
Medicine & Health / Neuroscience
Jul 18, 2011 |
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Overlooked peptide reveals clues to causes of Alzheimer's disease
Researchers at the RIKEN Brain Science Institute (BSI) and their collaborators have shed light on the function of a little-studied amyloid peptide in promoting Alzheimer's disease (AD). Their surprising findings reveal that ...
Medicine & Health / Neuroscience
Jul 03, 2011 |
4 / 5 (3) |
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Weight loss after gastric bypass surgery reduces expression of Alzheimer's genes
Obesity is a risk factor for Alzheimer's disease, but weight loss due to bariatric surgery may reduce the risk of this common dementia, a new study suggests. The results will be presented Sunday at The Endocrine Society's ...
Jun 06, 2011 |
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Increasing brain enzyme may slow Alzheimer's disease progression
Increasing puromycin-sensitive aminopeptidase, the most abundant brain peptidase in mammals, slowed the damaging accumulation of tau proteins that are toxic to nerve cells and eventually lead to the neurofibrillary ...
Feb 16, 2011 |
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Probing the secrets of sharp memory in old age
A study of the brains of people who stayed mentally sharp into their 80s and beyond challenges the notion that brain changes linked to mental decline and Alzheimer's disease are a normal, inevitable part of ...
Mar 23, 2010 |
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Promising new neuroimaging techniques for early detection of Alzheimer's disease
Investigators from the International Center for Biomedicine and the University of Chile, in collaboration with the Center for Bioinformatics of the Universidad de Talca, have discovered that two drugs, the benzimidazole derivatives ...
Jan 29, 2010 |
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Mechanism of Alzheimer's suggests combination therapy needed
Researchers at the University of Illinois at Chicago College of Medicine have discovered a mode of action for mysterious but diagnostic protein snarls found in the brains of Alzheimer's patients that suggests a one-two punch ...
Mar 17, 2009 |
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Scientists make headway in understanding Alzheimer's disease
Scientists at UC Santa Barbara have discovered that a protein called BAG2 is important for understanding Alzheimer's disease and may open up new targets for drug discovery. They are ready to move from studying ...
Feb 05, 2009 |
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Researchers See Complex Atomic Choreography as Crystals Melt
(PhysOrg.com) -- Conga lines of atoms wend their way through a crystal, their numbers growing as more and more atoms join the migration. The worm-like lines of atoms randomly converge, forming tangles that ...
Feb 02, 2009 |
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