News tagged with target cell
Parkinson's disease: Study of live human neurons reveals the disease's genetic origins
Parkinson's disease researchers at the University at Buffalo have discovered how mutations in the parkin gene cause the disease, which afflicts at least 500,000 Americans and for which there is no cure.
Feb 07, 2012 |
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How autoreactive T cells slip through the cracks
Immune cells capable of attacking healthy organs "see" their targets differently than do protective immune cells that attack viruses, according to work published online this week in the Journal of Experimental Medicine.
Feb 06, 2012 |
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A thought-provoking new therapeutic target for brain cancer?
Glioblastoma multiforme (GBM) is the most common of all malignant brain tumors that originate in the brain. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant ...
Feb 01, 2012 |
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Mutated Kras spins a molecular loop that launches pancreatic cancer
Scientists have connected two signature characteristics of pancreatic cancer, identifying a self-perpetuating "vicious cycle" of molecular activity and a new potential target for drugs to treat one of the most lehal forms ...
Jan 26, 2012 |
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Three is the magic number: A chain reaction required to prevent tumor formation
Protein p53 is known for controlling the life and death of a cell and has a key role in cancer research. P53 is known to be inactive in 50 percent of cancer patients. If researchers succeed in re-establishing the presence ...
Jan 20, 2012 |
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Chemists unlock potential target for drug development
A receptor found on blood platelets whose importance as a potential pharmaceutical target has long been questioned may in fact be fruitful in drug testing, according to new research from Michigan State University ...
Chemistry / Analytical Chemistry
Jan 19, 2012 |
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High risk oesophageal cancer gene discovered
New research from Queen Mary, University of London has uncovered a gene which plays a key role in the development of oesophageal cancer (cancer of the gullet).
Jan 19, 2012 |
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Some breast cancer spread may be triggered by a protein, study shows
Cancers rarely are deadly unless they evolve the ability to grow beyond the tissues in which they first arise. Normally, cells -- even early-stage tumor cells -- are tethered to scaffolding that helps to restrain ...
Jan 17, 2012 |
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Scientists characterize protein essential to survival of malaria parasite
A biology lab at Washington University has just cracked the structure and function of a protein that plays a key role in the life of a parasite that killed 655,000 people in 2010.
Jan 06, 2012 |
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New research finds trigger for breast cancer spread
Research led by Shyamal Desai, PhD, Assistant Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, has discovered a key change in the body's defense system that increases the potential ...
Jan 03, 2012 |
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Scientists reveal how bacteria build homes inside healthy cells
(PhysOrg.com) -- Bacteria are able to build camouflaged homes for themselves inside healthy cells - and cause disease - by manipulating a natural cellular process.
Dec 20, 2011 |
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Researchers identify agent responsible for protection against early stages of atherosclerosis
Researchers from Boston University School of Medicine (BUSM) have identified for the first time the A2b adenosine receptor (A2bAR) as a possible new therapeutic target against atherosclerosis resulting from a diet high in ...
Medicine & Health / Cardiology
Dec 12, 2011 |
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How patients will respond to immunomodulator therapy for multiple myeloma
Research on the same protein that was a primary mediator of the birth defects caused by thalidomide now holds hope in the battle against multiple myeloma, says the study's senior investigator, Keith Stewart, M.B., Ch.B. of ...
Dec 11, 2011 |
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New insights come from tracing cells that irreversibly scar lungs
Idiopathic Pulmonary Fibrosis (IPF) is an incurable disease in which the delicate gas exchange region of the lung fills with scar tissue, which interferes with breathing. Now researchers at Duke University Medical Center ...
Dec 01, 2011 |
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New 'Achilles' heel' in breast cancer: tumor cell mitochondria
Researchers at the Kimmel Cancer Center at Jefferson have identified cancer cell mitochondria as the unsuspecting powerhouse and "Achilles' heel" of tumor growth, opening up the door for new therapeutic targets in breast ...
Dec 01, 2011 |
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