News tagged with target genes
Researchers increase understanding of gene's potentially protective role in Parkinson's
Treatments for Parkinson's disease, estimated to affect 1 million Americans, have yet to prove effective in slowing the progression of the debilitating disease.
Medicine & Health / Neuroscience
Feb 07, 2012 |
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Parkinson's disease: Study of live human neurons reveals the disease's genetic origins
Parkinson's disease researchers at the University at Buffalo have discovered how mutations in the parkin gene cause the disease, which afflicts at least 500,000 Americans and for which there is no cure.
Feb 07, 2012 |
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Three is the magic number: A chain reaction required to prevent tumor formation
Protein p53 is known for controlling the life and death of a cell and has a key role in cancer research. P53 is known to be inactive in 50 percent of cancer patients. If researchers succeed in re-establishing the presence ...
Jan 20, 2012 |
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High risk oesophageal cancer gene discovered
New research from Queen Mary, University of London has uncovered a gene which plays a key role in the development of oesophageal cancer (cancer of the gullet).
Jan 19, 2012 |
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Unexpected discovery opens up new opportunities for targeting cancer
Scientists at the University of Leicester have opened up a whole new approach to the therapeutic intervention for a family of anti-cancer drug targets, thanks to a completely new and unexpected finding.
Jan 10, 2012 |
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Researchers map potential genetic origins, pathways of lung cancer in nonsmokers
Researchers at the Translational Genomics Research Institute (TGen) have begun to identify mutations and cellular pathway changes that lead to lung cancer in never-smokers -- a first step in developing potential therapeutic ...
Jan 09, 2012 |
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A second 'bad' gene is linked to damaged cell buildup, paralysis in ALS
Following a major Northwestern Medicine breakthrough that identified a common converging point for all forms of amyotrophic lateral sclerosis (ALS and Lou Gehrig's disease), a new finding from the same scientists further ...
Nov 21, 2011 |
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Antifolates show promise against NSCLC subtype
Patients with non-small cell lung cancer who have mutations in the KRAS gene should respond well to the antifolate class of drugs, according to results of a recent study conducted by Quintiles comparing human lung cancer ...
Nov 14, 2011 |
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Signaling pathway linked to inflammatory breast cancer may drive disease metastasis
Amplification of anaplastic lymphoma kinase, which has been reported in other cancers such as non-small cell lung cancers, may be a primary driver of the rapid metastasis that patients with inflammatory breast cancer experience.
Nov 13, 2011 |
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Tamoxifen resistance -- and how to defeat it
In the last three decades, thousands of women with breast cancer have taken the drug tamoxifen, only to discover that the therapy doesn't work, either because their tumors do not respond to the treatment at all, or because ...
Nov 13, 2011 |
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Ohio State researchers design a viral vector to treat a genetic form of blindness
Researchers at Ohio State University Medical Center and Nationwide Children's Hospital have developed a viral vector designed to deliver a gene into the eyes of people born with an inherited, progressive form of blindness ...
Nov 02, 2011 |
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We are not only eating 'materials', we are also eating 'information'
In a new study, Chen-Yu Zhang's group at Nanjing university present a rather striking finding that plant miRNAs could make into the host blood and tissues via the route of food-intake. Moreover, once inside the host, they ...
Sep 19, 2011 |
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Scab resistance in durum wheat
Durum wheat is a valuable cereal crop widely used for human consumption in the United States, Canada, and several European countries. Scab or Fusarium head blight is one of the crop's most serious diseases, reducing its grain ...
Sep 16, 2011 |
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Gene therapy kills breast cancer stem cells, boosts chemotherapy
Gene therapy delivered directly to a particularly stubborn type of breast cancer cell causes the cells to self-destruct, lowers chance of recurrence and helps increase the effectiveness of some types of chemotherapy, researchers ...
Sep 12, 2011 |
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Promising target in treating and preventing the progression of heart failure identified
Researchers at Mount Sinai School of Medicine have identified a new drug target that may treat and/or prevent heart failure. The team evaluated failing human and pig hearts and discovered that SUMO1, a so-called "chaperone" ...
Medicine & Health / Cardiology
Sep 07, 2011 |
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