Myelotoxicity is the primary dose-limiting effect of the commonly used chemotherapeutic agent 5-fluorouracil (5-FU), which may endanger the life of the patient. Ribosome biogenesis is a key pathway regulating hematopoietic ...
Cell & Microbiology
Aug 8, 2023
0
5
The key to understanding proteins—such as those that govern cancer, COVID-19, and other diseases—is quite simple: Identify their chemical structure and find which other proteins can bind to them. But there's a catch.
Biotechnology
Aug 3, 2023
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77
Discovering and developing drugs can be slow, costly and high-risk, but harnessing advances in artificial intelligence (AI) can help with these processes, say Brock University researchers.
Molecular & Computational biology
Aug 1, 2023
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30
Scientists from the Giulio Superti-Furga Lab at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, have developed a new method that allows the discovery of specific inhibitors of a lactate ...
Cell & Microbiology
Jul 28, 2023
0
5
Drawing inspiration from natural sensory systems, an MIT-led team has designed a novel sensor that could detect the same molecules that naturally occurring cell receptors can identify.
Biotechnology
Jul 21, 2023
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76
Scientists have engineered adeno-associated viruses (AAVs) to package and deliver gene therapies to cells in the body. But the field has struggled to develop AAVs that can efficiently target different cell types and organs ...
Biotechnology
Jul 20, 2023
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28
In a new study, researchers from IBM, Oxford University and Diamond Light Source show that IBM's AI Model, MoLFormer, can generate antiviral molecules for multiple target virus proteins, including SARS-CoV-2, that can accelerate ...
Biochemistry
Jun 28, 2023
0
7
Researchers at the University of Helsinki, together with researchers from the United States, have discovered a small molecule that inhibits the formation in cells of cytokine proteins that promote inflammation. The mechanism ...
Biochemistry
Jun 7, 2023
0
40
Recently, a research team led by Prof. Sun Baolin from the University of Science and Technology of China (USTC) revealed the mechanism of transcriptional regulation via S-nitrosylation for vancomycin resistance in Staphylococcus ...
Cell & Microbiology
May 31, 2023
0
6
The first protein-based nano-computing agent that functions as a circuit has been created by Penn State researchers. The milestone puts them one step closer to developing next-generation cell-based therapies to treat diseases ...
Bio & Medicine
May 26, 2023
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