Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that telomeres that protect the ends ...
Molecular & Computational biology
Feb 28, 2024
0
244
The natural ends of chromosomes appear alarmingly like broken DNA, much as a snapped spaghetti strand is difficult to distinguish from its intact counterparts. Yet every cell in our bodies must have a way of differentiating ...
Cell & Microbiology
Feb 15, 2024
0
64
For the very first time, a study led by Julian Chen and his group in Arizona State University's School of Molecular Sciences and the Biodesign Institute's Center for the Mechanism of Evolution, has discovered an unprecedented ...
Molecular & Computational biology
Oct 3, 2022
0
2302
The Wake Forest Institute for Regenerative Medicine (WFIRM) researchers, who were the first to identify that stem cells in human urine have potential for tissue regenerative effects, continue their investigation into the ...
Cell & Microbiology
Jun 28, 2022
2
687
A telomere is a region of repetitive nucleotide sequences associated with specialized proteins located at the ends of linear eukaryotic chromosomes to protect the chromosomes from progressive degradation and ensure its integrity. ...
Cell & Microbiology
Nov 26, 2021
0
119
Telomeres are large nucleoproteins structures that cap the ends of chromosomes in eukaryotic cells. When a cell divides, a small portion of the telomere is lost due to the inherently incomplete process of genome replication. ...
Biotechnology
Apr 22, 2021
0
197
Canadian scientists have achieved a first in the study of telomerase, an essential enzyme implicated in aging and cancer.
Molecular & Computational biology
Jun 3, 2020
0
51
Stem cells involved in replenishing human tissues and blood depend on an enzyme known as telomerase to continue working throughout our lives. When telomerase malfunctions, it can lead to both cancer and premature aging conditions. ...
Molecular & Computational biology
Mar 3, 2020
1
197
One of the hallmarks of cancer is cell immortality. A Northwestern University organic chemist and his team now have developed a promising molecular tool that targets and inhibits one of cell immortality's underlying gears: ...
Biochemistry
Mar 3, 2020
2
962
The oldest living organism on Earth is a plant, Methuselah a bristlecone pine (Pinus longaeva) that is over 5000 years old. Conversely, animals only live up to a few hundred years. Can we learn something from plants about ...
Molecular & Computational biology
Nov 18, 2019
1
195
