The blood-brain barrier blocks the entry of antibodies into the brain. This limits the potential use of antibody therapeutics to treat brain diseases, such as brain tumors.
Bio & Medicine
Jan 3, 2024
0
74
An array of different mutations or combinations of mutations may help the omicron variant of SARS-CoV-2 escape immune responses or therapeutic antibodies, according to a study published today in eLife.
Evolution
Feb 22, 2023
0
25
Scientists at The University of Texas MD Anderson Cancer Center and Northwestern Medicine have identified natural extracellular vesicles containing the ACE2 protein (evACE2) in the blood of COVID-19 patients that can block ...
Bio & Medicine
Jan 20, 2022
0
1205
Modern anticancer therapies aim to attack tumor cells while sparing healthy tissue. An interdisciplinary team of researchers at Helmholtz-Zentrum Dresden-Rossendorf (HZDR) and FU Berlin has made important progress in this ...
Bio & Medicine
Feb 24, 2020
0
2
Therapeutic antibodies are increasingly being used in the clinic for the treatment of diseases. Yet, oral to gut targeting of antibodies remains a challenge due to their inability to survive digestion and reach gastrointestinal ...
Cell & Microbiology
Apr 1, 2019
0
115
Scientists from the German Cancer Research Center (DKFZ) have succeeded in reconstructing biomolecules in their mirror-image form. The researchers' goal is to create a mirror-image artificial protein synthesis system. Their ...
Biochemistry
Mar 14, 2019
0
49
Differences in production methods for therapeutic antibodies can lead to variations in their structure, depending on the recombinant procedure selected. The distinctions, which are based on a number of glycosylations, even ...
Biochemistry
Jul 10, 2018
0
10
Tailor-made protein drugs in the fight against cancer and other diseases are a step close, with the Centre for NanoScale Science and Technology at Flinders playing a part in one of the latest chemistry discoveries in effectively ...
Biochemistry
Mar 9, 2018
0
186
Researchers at Eindhoven University of Technology (TU/e) present a new method for controlled drug delivery into the bloodstream using DNA computers. In the journal Nature Communications, the team, led by biomedical engineer ...
Biotechnology
Feb 17, 2017
0
19
Monoclonal antibodies, proteins that bind to and destroy foreign invaders in our bodies, routinely are used as therapeutic agents to fight a wide range of maladies including breast cancer, leukemia, asthma, arthritis, psoriasis, ...
Biochemistry
Aug 31, 2015
2
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