News tagged with topoisomerase


Secrets revealed about how disease-causing DNA mutations occur

Secrets revealed about how disease-causing DNA mutations occur

Biology / Cell & Microbiology

created Jul 02, 2009 | popularity 5 / 5 (2) | comments 0

A team of Penn State scientists has shed light on the processes that lead to certain human DNA mutations that are implicated in hundreds of inherited diseases such as tuberous sclerosis and neurofibromatosis ...


Gene alterations associated with response to anthracycline therapy for breast cancer

Medicine & Health / Cancer

created Apr 28, 2009 | popularity not rated yet | comments 0

Alterations in the topoisomerase II alpha (TOP2A) gene were associated with better patient outcomes following anthracycline-based therapy compared with non-anthracycline-based regimens, according to a study in the April ...





Search results for topoisomerase


DNA with a twist: New company to search for cancer drugs and antibiotics

DNA with a twist: New company to search for cancer drugs and antibiotics

Medicine & Health / Cancer

created Feb 13, 2008 | popularity not rated yet | comments 0

A new company has joined the fight against MRSA and cancer. Researchers at the John Innes Centre (Norwich) have launched a new company, Inspiralis Ltd, based around their expertise in DNA topoisomerases – ...


Nanotweezers Unlock Anticancer Drug Secrets

Nanotechnology / Bio & Medicine

created Aug 22, 2007 | popularity 4.4 / 5 (13) | comments 0

The annoying bulges of an overwound telephone cord that shorten its reach and limit a caller’s motion help explain why drugs called camptothecins are so effective in killing cancer cells, according to investigators led by ...


Tiny tweezers and yeast help researchers show how cancer drug works

Nanotechnology / Bio & Medicine

created Jul 09, 2007 | popularity 4.5 / 5 (6) | comments 0

The annoying bulges of an over-wound telephone cord that shorten its reach and limit a caller’s motion help to explain why drugs called camptothecins are so effective in killing cancer cells, according to investigators at ...


First look at an enzyme target for antibacterial and cancer drugs

First look at an enzyme target for antibacterial and cancer drugs

Biology /

created Dec 20, 2007 | popularity 4.7 / 5 (7) | comments 0

The veil has finally been lifted on an enzyme that is critical to the process of DNA transcription and replication, and is a prime target of antibacterial and anticancer drugs. Researchers with the U.S. Department ...


Soy peptide lunasin has anti-cancer, anti-inflammatory properties

Chemistry / Biochemistry

created Dec 02, 2009 | popularity not rated yet | comments 0

Two new University of Illinois studies report that lunasin, a soy peptide often discarded in the waste streams of soy-processing plants, may have important health benefits that include fighting leukemia and blocking the inflammation ...



List of search results for topoisomerase