In a recent article published in Molecular Cell, Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, and Yuki Aoi Ph.D., a postdoctoral fellow in Shilatifard laboratory, ...
Cell & Microbiology
Nov 3, 2023
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66
Jasmonate is a critical phytohormone that regulates plant development and adaptation to external conditions. In response to an exposure biotic or abiotic stress, jasmonate accumulates in plants, leading to root growth inhibition ...
Plants & Animals
Nov 14, 2022
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25
Northwestern Medicine investigators have discovered novel mechanisms underlying a specific transcription factor essential for elongation control, the process of synthesizing RNA from DNA, according to findings published in ...
Cell & Microbiology
Aug 11, 2022
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13
A genetically encoded "live-cell" probe designed by researchers from Tokyo Tech has been able to identify phosphorylated Ser2 in the enzyme RNA polymerase II, subsequently identifying sites of the elongation phase of active ...
Cell & Microbiology
Dec 2, 2021
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81
A team led by researchers at Baylor College of Medicine and the Czech Academy of Sciences has uncovered a new piece of the puzzle of how gene expression is orchestrated. Published in the journal Science, the findings reveal ...
Biotechnology
Nov 25, 2021
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89
Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in Molecular Cell.
Molecular & Computational biology
Sep 6, 2021
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99
A little-studied factor known as the Little Elongation Complex (LEC) plays a critical and previously unknown role in the transcription of small nuclear RNAs (snRNA), according to a new study led by scientists at the Stowers ...
Cell & Microbiology
Aug 8, 2013
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0
By way of mechanical stretching, National University of Singapore researchers identify a novel double-stranded DNA structure, thus successfully resolving a 16-year-old scientific debate over the existence of a double-stranded ...
Biotechnology
Aug 3, 2012
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0
Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in the process that ...
Cell & Microbiology
Dec 22, 2011
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0
Just like orchestra musicians waiting for their cue, RNA polymerase II molecules are poised at the start site of many developmentally controlled genes, waiting for the "Go!"- signal to read their part of the genomic symphony. ...
Cell & Microbiology
Jul 14, 2011
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