News tagged with transcription
Researchers find important 'target' playing role in tobacco-related lung cancers
Researchers at Moffitt Cancer Center in Tampa, Fla., have discovered that the immune response regulator IKBKE (serine/threonine kinase) plays two roles in tobacco-related non-small cell lung cancers. Tobacco carcinogens induce ...
Feb 09, 2012 |
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CD97 gene expression and function correlate with WT1 protein expression and glioma invasiveness
Researchers at Virginia Commonwealth University Medical Center's VCU Massey Cancer Center and Harold F. Young Neurosurgical Center (Richmond, VA) and Old Dominion University (Norfolk, VA) have discovered that suppression ...
Medicine & Health / Neuroscience
Feb 07, 2012 |
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Drugs targeting chromosomal instability may fight a particular breast cancer subtype
Another layer in breast cancer genetics has been peeled back. A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD., FACP, Director of the KCC and Chair of the Department of ...
Feb 06, 2012 |
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Collective action: Occupied genetic switches hold clues to cells' history
If you wanted to draw your family tree, you could start by searching for people who share your surname. Cells, of course, don't have surnames, but scientists at the European Molecular Biology Laboratory (EMBL) ...
Feb 03, 2012 |
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Weightlessness weighs heavy on genes -- a fly's perspective
On Earth all biology is subjected to gravity. Some biological systems require gravity for correct orientation (geotropism: plants grow up, roots grow down). In the absence of gravity even human biology is affected: astronauts ...
Jan 31, 2012 |
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Researchers turn skin cells into neural precusors, bypassing stem-cell stage
Mouse skin cells can be converted directly into cells that become the three main parts of the nervous system, according to researchers at the Stanford University School of Medicine. The finding is an extension of a previous ...
Jan 30, 2012 |
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SUMO-snipping protein plays crucial role in T and B cell development
When SUMO grips STAT5, a protein that activates genes, it blocks the healthy embryonic development of immune B cells and T cells unless its nemesis breaks the hold, a research team led by scientists at The University of Texas ...
Jan 27, 2012 |
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'DIMming' cancer growth -- STAT: Diindolylmethane suppresses ovarian cancer
Ovarian cancer is a major cause of death worldwide. Approximately 25,000 women will be diagnosed with ovarian cancer this year and 15,000 women will die from it in the United States alone. The novel anti-cancer drug diindolylmethane ...
Jan 26, 2012 |
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Improving crops from the roots up
Research involving scientists at The University of Nottingham has taken us a step closer to breeding hardier crops that can better adapt to different environmental conditions and fight off attack from parasites.
Jan 24, 2012 |
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Scientists uncover novel mechanism of glioblastoma development
Most research on glioblastoma development, a complicated tumor of the brain with a poor prognosis, has focused on the gene transcription level, but scientists suggest that post-transcriptional regulation could be equally ...
Jan 18, 2012 |
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Study uncovers how DNA unfolds for transcription
(PhysOrg.com) -- The human genome contains some 3 billion base pairs that are tightly compacted into the nucleus of each cell. If a DNA strand were the thickness of a human hair, the entire human genome would ...
Jan 17, 2012 |
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Research team discovers genes and disease mechanisms behind a common form of muscular dystrophy
Continuing a series of groundbreaking discoveries begun in 2010 about the genetic causes of the third most common form of inherited muscular dystrophy, an international team of researchers led by a scientist at Fred Hutchinson ...
Jan 12, 2012 |
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Signaling to chromatin
(Medical Xpress) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI) in collaboration with their colleagues from the Department of Biosystems Science and Engineering of the ETH ...
Jan 03, 2012 |
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Mutation in gene that's critical for human development linked to arrhythmia
Arrhythmia is a potentially life-threatening problem with the rate or rhythm of the heartbeat, causing it to go too fast, too slow or to beat irregularly. Arrhythmia affects millions of people worldwide.
Dec 27, 2011 |
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New light shed on chromosome fragility
Why are certain chromosome regions prone to breakages? The answer is crucial, as this fragility is involved in the development of tumors. A team from the Institut de Génétique et de Biologie Moleculaire et Cellulaire ...
Dec 26, 2011 |
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