News tagged with transcriptional activators
Small molecules mimic natural gene regulators
Jun 03, 2009 |
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(PhysOrg.com) -- In the quest for new approaches to treating and preventing disease, one appealing route involves turning genes on or off at will, directly intervening in ailments such as cancer and diabetes, which result ...
Search results for transcriptional activators
Toward new drugs that turn genes on and off
Jun 04, 2009 |
5 / 5 (6) |
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Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, ...
Stem-cell activators switch function, repress mature cells
Dec 16, 2009 |
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In a developing animal, stem cells proliferate and differentiate to form the organs needed for life. A new study shows how a crucial step in this process happens and how a reversal of that step contributes to cancer.
Leukemia stem cells have more in common with embryonic stem cells than adult stem cells
Biology /
Feb 05, 2009 |
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Research using a mouse model of human leukemia has provided critical insight into the genetic factors related to the generation and maintenance of myeloid leukemia stem cells. The study, published by Cell Press in the February ...
A potential new target for treatment of hormone refractory prostate cancer
Apr 06, 2009 |
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A new study identifies a protein that modifies the androgen receptor (AR) and influences its ability to regulate target genes linked with the progression of prostate cancer. The research, published by Cell Press in the April ...
Memories of the way they used to be
Sep 18, 2009 |
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A team of researchers from the University of California, San Diego School of Medicine and the Salk Institute for Biological Studies in La Jolla have developed a safe strategy for reprogramming cells to a pluripotent ...
Gene linked with human kidney aging
Oct 16, 2009 |
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A gene has been associated with human kidney aging, according to researchers from Stanford University, the National Institute on Aging, the MedStar Research Institute, and the HudsonAlpha Institute for Biotechnology. In work ...
Future diabetes treatment may use resveratrol to target the brain
Oct 06, 2009 |
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Resveratrol, a molecule found in red grapes, has been shown to improve diabetes when delivered orally to rodents. Until now, however, little has been known about how these beneficial changes are mediated in the body. A new ...
Misreading of damaged DNA may spur tumor formation
Nov 20, 2008 |
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The DNA in our cells is constantly under assault from oxygen, the sun's radiation and environmental stresses. Most of the time, our cells can repair the damage before it gets copied into a permanent mutation that could lead ...
New papers offer insights into process of malarial drug resistance
Biology /
Nov 26, 2008 |
4.5 / 5 (2) |
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Malaria, one of the oldest diseases known to man, has shown no signs of slowing down as it ages. More than 1 million children die from malaria in sub-Saharan Africa each year, and in areas along the Thailand/Cambodian border ...
Researchers unlock how cells determine their functions
Feb 27, 2006 |
4.9 / 5 (9) |
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Researchers at the University of California, Riverside have discovered a molecular mechanism directing the fate and function of cells during animal development. The findings could hold promise for the advancement of cancer ...
List of search results for transcriptional activators
