News tagged with tumor formation
The proteins ensuring genome protection
Researchers from the University of Geneva (UNIGE), Switzerland, have discovered the crucial role of two proteins in developing a cell 'anti-enzyme shield'. This protection system, which operates at the level of molecular ...
Feb 12, 2012 |
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Why cholesterol-lowering statins might treat cancer
Cholesterol-lowering statins seem to keep breast cancer at bay in some patients. Now researchers reporting in the January 20th issue of the journal Cell, a Cell Press publication, provide clues about how statins might yield ...
Jan 19, 2012 |
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Scientists uncover novel mechanism of glioblastoma development
Most research on glioblastoma development, a complicated tumor of the brain with a poor prognosis, has focused on the gene transcription level, but scientists suggest that post-transcriptional regulation could be equally ...
Jan 18, 2012 |
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Previously unconnected molecular networks conspire to promote cancer
An inflammation-promoting protein triggers deactivation of a tumor-suppressor that usually blocks cancer formation via the NOTCH signaling pathway, a team of researchers led by scientists at The University of Texas MD Anderson ...
Dec 22, 2011 |
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Pig-induced pluripotent stem cells may be safer than previously thought
Pig stem cell research conducted by two animal scientists at the University of Georgia reveals a better way to determine the safety of future stem cell therapies than rodent-based models.
Dec 09, 2011 |
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Cell molecule identified as central player in the formation of new blood vessels
Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified a cellular protein that plays a central role in the formation of new blood vessels. The molecule is the protein ...
Nov 28, 2011 |
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Study identifies a key molecular switch for telomere extension by telomerase
Researchers at the University of Illinois at Chicago College of Medicine describe for the first time a key target of DNA damage checkpoint enzymes that must be chemically modified to enable stable maintenance of chromosome ...
Nov 23, 2011 |
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New study identifies novel role for PEA-15 protein in cancer growth
A new study from the University of Hawaii Cancer Center reveals that PEA-15, a protein previously shown to slow ovarian tumor growth and metastasis, can alternatively enhance tumor formation in kidney cells carrying a mutation ...
Nov 21, 2011 |
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Researchers develop more effective way to discover and test potential cancer drugs
Researchers have created a new phenotypic screening platform that better predicts success of drugs developed to prevent blood vessel tumor growth when moving out of the lab and onto actual tumors.
Nov 13, 2011 |
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Combination therapy shows potent tumor growth inhibition in preclinical studies
Combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in antitumor effects in animal models compared with either agent alone, according to results presented at the AACR-NCI-EORTC ...
Nov 13, 2011 |
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New role for Vascular Endothelial Growth Factor in regulating skin cancer stem cells
Skin squamous cell carcinomas are amongst the most frequent cancers in humans. Recent studies suggest that skin squamous cell carcinoma, like many other human cancers, contain particular cancer cells, known as cancer stem ...
Oct 19, 2011 |
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Genetic differences may cause higher rates of prostate cancer in African-American men
Genetic differences in prostate cells seem to be a root cause of the prostate cancer disparities between African-American men and white men, according to findings presented at the Fourth AACR Conference on The Science of ...
Sep 20, 2011 |
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Gene found to play role in early cancer
(Medical Xpress) -- Mutations to a gene called p53 have been linked to half of all cancers, leading to tumor growth and the spread of cancerous cells. Now, a Cornell-led study identifies for the first time the mechanisms ...
Aug 24, 2011 |
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Researchers gain new insights into how tumor cells are fed
Philadelphia, PA, August 8, 2011 – Researchers have gained a new understanding of the way in which growing tumors are fed and how this growth can be slowed via angiogenesis inhibitors that eliminate the blood supply ...
Aug 08, 2011 |
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Slow growth of childhood brain tumors explained
(Medical Xpress) -- Johns Hopkins researchers have found a likely explanation for the slow growth of the most common childhood brain tumor, pilocytic astrocytoma. Using tests on a new cell-based model of the tumor, they ...
Jun 23, 2011 |
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